Antibody specificity is the ability of an antibody to recognize and bind selectively to one particular antigen, or to a closely related set of antigens, rather than to molecules in general. This selectivity arises from the antibody's variable regions, whose unique three-dimensional shape is complementary to a specif…
Antibody specificity is the ability of an antibody to recognize and bind selectively to one particular antigen, or to a closely related set of antigens, rather than to molecules in general. This selectivity arises from the antibody's variable regions, whose unique three-dimensional shape is complementary to a specific portion of the antigen known as the epitope. Specificity is fundamental to the immune system, allowing antibodies to target particular pathogens or foreign substances while sparing the body's own tissues, and it underpins immunological memory and protection following infection or vaccination. The same property makes antibodies indispensable laboratory and clinical tools, because their precise binding enables them to identify and measure defined targets in diagnostic and research assays. Within the broad biomedical scope reflected on this page, related work includes studies employing immunoassay technologies for monitoring cancer and infectious diseases and an account of the evolution of the enzyme immunoassay and enzyme-linked immunosorbent assay (ELISA), techniques whose accuracy depends directly on antibody specificity. This page gathers peer-reviewed, open-access research relevant to antibody specificity and the immunological and analytical methods that rely on selective antigen recognition.
7 peer-reviewed articles, ranked by relevance. Each links to its DOI.
The 7 articles above have been cited 16 times in the scholarly literature. Citation data via OpenAlex and Crossref, updated Jun 2026.
A sample of recent works citing this journal's research on Antibody Specificity, linking to each citing work.