Epilepsy in Paget's

disease Epilepsy in Paget's disease is a neurological disorder that causes seizures, or episodes of uncontrolled electrical activity in the brain, due to abnormal bone growth. It is characterized by an increase in bone turnover, resulting in enlarged and deformed bones. Epilepsy in Paget's disease is a rare form of the disorder, affecting approximately 1 to 5 percent of those with Paget's disease. It is typically diagnosed in elderly individuals, with typical onset between the ages of 50 and 70 years. Treatment for epilepsy in Paget's disease includes the use of antiepileptic medications, such as carbamazepine and lamotrigine, as well as surgical procedures, such as corpus callosotomy and temporal lobectomy. These treatments are often able to reduce the frequency and severity of seizures. Additionally, lifestyle measures, such as avoiding overly stressful and stimulating activities, can be helpful in managing the symptoms of epilepsy in Paget's disease.