Research Topic · Peer-Reviewed

Pathophysiology

Pathophysiology is the study of the disordered physiological processes and functional changes that accompany or result from disease, providing the mechanistic link between etiology and the clinical manifestations a patient presents. It integrates physiology, biochemistry, molecular biology and pathology to explain h…

Curated from this journal's research 📚 12 peer-reviewed articles cited Cited 31× across the literature 🔖 ISSN 2329-9487

Overview

Pathophysiology is the study of the disordered physiological processes and functional changes that accompany or result from disease, providing the mechanistic link between etiology and the clinical manifestations a patient presents. It integrates physiology, biochemistry, molecular biology and pathology to explain how normal regulatory systems are disrupted, how compensatory mechanisms are recruited, and how these alterations progress to symptoms, complications and organ dysfunction. In the cardiovascular context, pathophysiology addresses the mechanisms underlying hypertension, heart failure, ischemia, vascular remodelling and arrhythmogenesis, including neurohormonal activation, endothelial dysfunction, altered signalling and structural adaptation of the heart and vessels. Studies in this area examine cardiac physiology and pathophysiology in relation to factors such as menopausal status, the regulatory role of microRNAs in hypertension, cardiorenal signalling in heart failure, and cardiovascular responses to hypoxia and high-altitude exposure. Related work considers the contribution of immune mechanisms to frailty and the systemic processes that modify disease expression. By identifying the specific functional derangements that drive a condition, pathophysiological analysis underpins diagnosis, defines therapeutic targets and clarifies why interventions succeed or fail, connecting basic mechanism to bedside presentation across acute and chronic cardiovascular disorders.

Research published in this journal

12 peer-reviewed articles, ranked by relevance. Each links to its DOI.

2014

Hypertension in Hypoxia

Prasenjit GuchhaitCorresponding author
Exact topic Journal of Hypertension and Cardiology doi:10.14302/issn.2329-9487.jhc-14-edt3
2017

Frailty and the Immune System

Daisy WilsonCorresponding author
Exact topic Journal of Aging Research and Healthcare Cited by 19 doi:10.14302/issn.2474-7785.jarh-17-1578

How this research is being cited

The 12 articles above have been cited 31 times in the scholarly literature. Citation data via OpenAlex and Crossref, updated Nov 2026.

A sample of recent works citing this journal's research on Pathophysiology, linking to each citing work.

Editorial oversight

Curated from peer-reviewed research published in Journal of Hypertension and Cardiology (ISSN 2329-9487).

Journal editorial board
Hatori Nobuo · Japan Sandeep Kumar Kar · India Gregor Leibundgut · Switzerland

This page summarises published research for orientation; it is not medical or professional advice.