Research Topic · Peer-Reviewed

Invasive Lobular Carcinoma

Invasive lobular carcinoma (ILC) is a type of breast cancer that originates in the lobules, the milk-producing glands of the breast, and then invades surrounding tissue. It is the second most common form of invasive breast cancer after invasive ductal carcinoma, accounting for roughly one in ten cases. ILC is distin…

Curated from this journal's research 📚 2 peer-reviewed articles cited Cited 1× across the literature 🔖 ISSN 2372-6601 🗓 Reviewed June 2026

Overview

Invasive lobular carcinoma (ILC) is a type of breast cancer that originates in the lobules, the milk-producing glands of the breast, and then invades surrounding tissue. It is the second most common form of invasive breast cancer after invasive ductal carcinoma, accounting for roughly one in ten cases. ILC is distinguished by its characteristic growth pattern, in which tumour cells spread in single-file lines through the breast tissue, often producing a diffuse rather than a discrete lump. This pattern can make ILC harder to detect on mammography and clinical examination and can complicate assessment of tumour extent. The great majority of lobular carcinomas express hormone receptors, which influences treatment with endocrine therapy alongside surgery, radiation, and systemic options. As a research subject, ILC sits within breast and gynaecological oncology, where molecular characterisation and biomarkers guide prognosis and therapy. Hematology and Oncology Research covers cancer biology and treatment, including a study correlating the Oncotype DX recurrence score with the expression of insulin receptor substrate proteins in estrogen-receptor-positive breast cancer, work relevant to prognostic testing in hormone-receptor-positive disease. This page gathers peer-reviewed, open-access research relevant to invasive lobular carcinoma and breast cancer biology.

Research published in this journal

2 peer-reviewed articles, ranked by relevance. Each links to its DOI.

How this research is being cited

The 2 articles above have been cited 1 time in the scholarly literature. Citation data via OpenAlex and Crossref, updated Jun 2026.

A sample of recent works citing this journal's research on Invasive Lobular Carcinoma, linking to each citing work.

Editorial oversight

Curated from peer-reviewed research published in Hematology and Oncology Research (ISSN 2372-6601).

Journal editorial board
Jayadev Manikkam Umakanthan · United States Shuaiying Cui · United States Benedetto Sacchetti · Italy

This page summarises published research for orientation; it is not medical or professional advice.