Overview
Hepatocellular carcinoma is a type of liver cancer that is associated with the formation of malignant hepatocytes. This type of cancer is also sometimes referred to as hepatoma. Hepatocellular carcinoma accounts for approximately 80% of all primary liver cancers and is the leading cause of death in patients with liver cirrhosis. The development of hepatocellular carcinoma is strongly associated with risk factors such as chronic hepatitis B and C infections, cirrhosis, alcohol abuse, and exposure to environmental toxins. Certain genetic conditions and metabolic disorders are also known to increase the risk of developing this type of cancer. Diagnosis of hepatocellular carcinoma typically involves a combination of medical history, physical examination, blood tests, ultrasound imaging, and biopsy. Treatment options for hepatocellular carcinoma may include surgical resection, liver transplantation, chemotherapy, radiotherapy, and targeted therapy. The choice of treatment will depend on factors such as the stage and location of the cancer, as well as the overall health of the patient. Research in the field of hematology and oncology is focused on developing new treatments and improving the understanding of the underlying mechanisms that contribute to the development and progression of hepatocellular carcinoma. This includes studies of genetic and molecular markers, risk factors, and the development of new diagnostic and treatment approaches. In summary, hepatocellular carcinoma is a serious and potentially lethal form of liver cancer that is associated with a number of risk factors. Early detection and treatment are critical for improving patient outcomes, and ongoing research is essential to improving our understanding of this complex disease.
Research published in this journal
12 peer-reviewed articles, ranked by relevance. Each links to its DOI.
How this research is being cited
The 12 articles above have been cited 42 times in the scholarly literature. Citation data via OpenAlex and Crossref, updated Jun 2026.
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2026 · BioMed Research International
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2025 · BMC Genomics
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2025 · BMC Gastroenterology
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2025 · BMC Gastroenterology
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2025 · Journal of Liver Cancer
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2024 · Risk Management and Healthcare Policy
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2024 · Journal of Environmental Pathology, Toxicology and Oncology
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2024 · Risk Management and Healthcare Policy
A sample of recent works citing this journal's research on Hepatocellular Carcinoma, linking to each citing work.