Gene Transfer for Anemia

Overview

Hematology and Oncology Research have been at the forefront of exploring novel gene transfer therapies for the treatment of various diseases. Anemia is one such condition that has been a target for gene therapy due to its widespread prevalence and the limitations of existing treatments. Gene transfer therapy for anemia works by introducing a functional copy of the faulty gene responsible for the condition. This can be achieved through various methods, such as viral vectors or non-viral approaches like CRISPR-Cas9 gene editing. The goal is to provide the patient's cells with the instructions to produce enough of the needed protein or correct the defective gene, thereby restoring the normal functioning of red blood cells. Apart from standard gene transfer approaches, there are now emerging technologies, such as RNA interference, which can silence the genes responsible for anemia. This approach has many advantages, including targeted effects, fewer off-target effects, and a relatively safer profile. The advantages of gene transfer for anemia are that it has the potential to provide long-lasting or even permanent therapeutic effects, reduce the need for chronic transfusions, and minimize the risk of complications such as iron overload, transfusion reactions, and infections. In conclusion, gene transfer therapy is an exciting field with great potential for revolutionizing the treatment of anemia. Research in this area shows promising results in experimental models and clinical trials, and novel therapies are likely to emerge in the near future. Clinicians and researchers must continue working together to develop safe and effective gene therapies, which can ultimately provide a cure for anemia.

Research published in this journal

2 peer-reviewed articles, ranked by relevance. Each links to its DOI.

How this research is being cited

The 2 articles above have been cited 3 times in the scholarly literature. Citation data via OpenAlex and Crossref, updated Jun 2026.

• CGRP expression and signaling sensitization in a mouse model of chronic oxaliplatin-induced peripheral neuropathy
  2026 · Molecular Pain
• Intrathyroidal Plasmacytoma with Pleomorphic Multilobated Bizarre Cells: A Rare Primary Clinicopathological Presentation Mimicking Anaplastic Carcinoma of Thyroid
  2022 · Head and Neck Pathology
• Intrathyroidal Plasmacytoma with Pleomorphic Multilobated Bizarre Cells: A Rare Primary Clinicopathological Presentation Mimicking Anaplastic Carcinoma of Thyroid
  2022 · Head and Neck Pathology

A sample of recent works citing this journal's research on Gene Transfer for Anemia, linking to each citing work.

This page summarises published research for orientation; it is not medical or professional advice.

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