Folate Deficiency

Folate deficiency is a condition that occurs when there is an insufficient amount of folate, which is a B vitamin essential for the proper functioning of the body. This condition can have serious health implications, as folate is responsible for various critical functions such as cell growth, DNA synthesis, and the formation of red and white blood cells. Folate deficiency can lead to specific medical concerns like megaloblastic anemia, a condition characterized by the enlargement of bone marrow cells and the production of fewer red blood cells, which results in tiredness, fatigue, and reduced oxygen supply to the organs. In addition to this, it can also increase the risk of neural tube defects in pregnant women, where the baby's brain and spinal cord do not develop correctly. The most common causes of folate deficiency are poor dietary habits, alcoholism, malabsorption syndromes, and medications like certain anticonvulsants, methotrexate, and sulfasalazine. Therefore, eating a diet rich in folate is essential, including leafy green vegetables, beans, and citrus fruits, which can help to prevent deficiency. Folate levels can also be managed through supplementation or the use of fortified foods commonly advertised as enriched with folic acid, the synthetic form of folate. Folate deficiency can cause significant complications, so staying informed and maintaining a healthy diet that includes necessary vitamins and minerals, can help prevent deficiencies and live a healthy life.


From: Hematology Research and Oncology Research

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