Research Topic · Peer-Reviewed

Coagulation Factors

Coagulation factors are proteins, mostly produced by the liver, that act in a regulated cascade to form blood clots and stop bleeding after injury. Each factor activates the next in sequence, ultimately converting fibrinogen to fibrin to stabilize a clot, and a balance of activating and inhibitory factors keeps clot…

Curated from this journal's research 📚 11 peer-reviewed articles cited Cited 25× across the literature 🔖 ISSN 2372-6601 🗓 Reviewed July 2026

Overview

Coagulation factors are proteins, mostly produced by the liver, that act in a regulated cascade to form blood clots and stop bleeding after injury. Each factor activates the next in sequence, ultimately converting fibrinogen to fibrin to stabilize a clot, and a balance of activating and inhibitory factors keeps clotting confined to sites of injury. Deficiencies or dysfunction of specific factors cause bleeding disorders such as the hemophilias, while excessive or unregulated activity contributes to thrombosis, making these proteins central to both hematology and oncology. In Hematology and Oncology Research, work directly relevant to coagulation factors includes a study of inherited bleeding disorders examining genetic mutations in blood coagulation factors and regulatory proteins, an analysis of hypercoagulability in patients with acute leukaemia, a case report and literature review of acquired haemophilia, and a report of Rosenthal's disease (factor XI deficiency) presenting as chronic epistaxis. Related work on haematological disturbances in dengue haemorrhagic fever addresses coagulation abnormalities in the setting of infection. Together these studies span inherited and acquired disorders of clotting factors and their links to malignancy. This page gathers peer-reviewed, open-access research relevant to coagulation factors and disorders of hemostasis.

Research published in this journal

11 peer-reviewed articles, ranked by relevance. Each links to its DOI.

How this research is being cited

The 11 articles above have been cited 25 times in the scholarly literature. Citation data via OpenAlex and Crossref, updated Jun 2026.

A sample of recent works citing this journal's research on Coagulation Factors, linking to each citing work.

Editorial oversight

Curated from peer-reviewed research published in Hematology and Oncology Research (ISSN 2372-6601).

Journal editorial board
Jayadev Manikkam Umakanthan · United States Shuaiying Cui · United States Benedetto Sacchetti · Italy

This page summarises published research for orientation; it is not medical or professional advice.