Chemoresistance

Chemoresistance is a major challenge faced by researchers in the fields of hematology and oncology. Chemotherapy is a commonly used strategy to treat cancer by targeting and killing cancer cells. However, some cancer cells may develop resistance to chemotherapy drugs, leading to treatment failure. Understanding the mechanisms of chemoresistance is crucial for improving cancer therapy and overcoming drug resistance. Several factors contribute to chemoresistance, including alterations in drug transport, metabolism and DNA repair mechanisms, as well as the presence of cancer stem cells. Cancer stem cells are a small population of cells within a tumor that have stem cell-like properties and can self-renew and differentiate into various cell types. These cells are often resistant to chemotherapy and radiation, making them a target for future therapies. Researchers in hematology and oncology are studying various approaches to overcome chemoresistance, such as the use of combination therapy, immunotherapy, targeted therapy, and nanotechnology-based drug delivery systems. These approaches aim to improve drug efficacy and reduce toxicity to healthy tissues. Furthermore, understanding the genetic and molecular mechanisms behind chemoresistance can allow for the development of personalized treatments for patients based on their individual tumor characteristics. In conclusion, chemoresistance is a challenging issue in hematology and oncology research. Researchers are investigating various strategies to overcome this resistance, which could lead to more effective cancer treatments and better outcomes for patients.


From: Hematology Research and Oncology Research

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Editor-in-chief: Krzysztof Roszkowski, Department of Oncology F. Lukaszczyk Oncology Center Nicolaus Copernicus University
Publication Type: Open Access Journal
Description: Hematology is a branch of medicine concerning the study of blood, the blood-forming organs, and blood diseases. The word "heme" comes from the Greek for blood. Oncology is a branch of medicine that deals with prevention, diagnosis and treatment of cancer. It is very important for oncologists to keep updated of the latest advancements in oncology.
Editor-in-chief: Cody Coyne, Department of Basic Sciences, College of Veterinary Medicine at Wise Center, Mississippi State University, Mississippi State, Mississippi 39762, USA.
Publication Type: Open Access Journal
Description: International Journal of Chemotherapy Research and Practice endeavors to develop Chemotherapy research by providing comprehensive information regarding recent developments in the field of Chemotherapy.