Illegitimate Recombination

Illegitimate recombination is a type of genetic recombination that does not involve DNA exchange between homologous chromosomes. It is a form of non-homologous end joining (NHEJ) that results in random rearrangements of the genome. Illegitimate recombination is an important source of genetic variation and has been implicated in the development of cancer, genetic diseases and antibiotic resistance. Additionally, illegitimate recombination is an important tool in genetic engineering, allowing scientists to create and study new genetic constructs, as well as to create genetically modified organisms (GMOs).