Overview
Pathogenic fungi are fungal species capable of causing disease in humans, animals, and plants, ranging from superficial infections of skin, hair, and nails to invasive, systemic, and life-threatening mycoses. They are conventionally grouped by the host tissues they colonize and the nature of infection: dermatophytes such as Microsporum and Trichophyton degrade keratin and cause superficial dermatophytoses; opportunistic yeasts and moulds, including Cryptococcus and members of the order Mucorales, produce deep infections that are especially dangerous in immunocompromised individuals, as seen in mucormycosis and cryptococcal meningitis. Keratinophilic and soil-borne fungi form important environmental reservoirs, while plant-pathogenic fungi such as Sclerotium cause substantial agricultural losses. Pathogenicity depends on virulence determinants including adhesion molecules, secreted hydrolytic and keratinolytic enzymes, thermotolerance, melanin and capsule production, and mechanisms for evading host immune defenses. Laboratory study relies on culture, microscopy, antigen assays, and increasingly molecular identification, often correlated with host biomarkers to gauge disease severity. Management combines antifungal pharmacotherapy with biological and natural control strategies, including plant-derived antimycotic extracts and biocontrol agents such as Trichoderma. Because resistance and host susceptibility complicate treatment, understanding the biology, ecology, and antifungal susceptibility of pathogenic fungi is central to medical mycology, veterinary medicine, and the broader study of Fungal Diversity.
Research published in this journal
5 peer-reviewed articles, ranked by relevance. Each links to its DOI.
Antimycotic Activity of Leaf Extracts of Medicinal Plants Against Dermatophytes
Evaluation of Organic and Vermi Composts for Mass Culturing of Trichoderma Harzianum to be Used Against Soil-Borne Pathogen Sclerotium Rolfsii of Groundnut
Correlation of Cryptococcal Antigen Assay with C-reactive Protein as Serum and Urine Biomarker in Cryptococcal Meningitis: Experience in a Tertiary Hospital
How this research is being cited
The 5 articles above have been cited 3 times in the scholarly literature. Citation data via OpenAlex and Crossref, updated Jun 2026.
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2025 · Research Journal of Pharmacy and Technology
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2025 · Research Journal of Pharmacy and Technology
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2021 · INTERNATIONAL JOURNAL OF ENDORSING HEALTH SCIENCE RESEARCH (IJEHSR)
A sample of recent works citing this journal's research on Pathogenic Fungi, linking to each citing work.