Overview
Prenatal diagnosis is the antenatal detection and characterization of structural, chromosomal, genetic, and functional abnormalities in the fetus, enabling informed counseling, pregnancy management, and planning for delivery and postnatal or fetal therapy. It combines imaging with sampling and molecular techniques: detailed and three-dimensional ultrasonography and Doppler angiography assess fetal anatomy, growth, and circulation, while invasive procedures such as amniocentesis and chorionic villus sampling provide fetal cells for cytogenetic and molecular testing. Increasingly, gene-level diagnosis—trio sequencing and identification of pathogenic mutations in disorders such as junctional epidermolysis bullosa, Tay-Sachs disease, inherited bleeding disorders, and multiple endocrine neoplasia—refines risk assessment and reproductive decision-making, raising attendant ethical considerations. Prenatal recognition of surgically relevant conditions, including congenital diaphragmatic hernia and fetal cystic lesions, allows prognostic stratification and identification of candidates for fetal intervention, linking diagnosis directly to Fetal Surgery and perinatal management. Accurate prognostication of malformations and assessment of fetal nutritional and physiological status further guide multidisciplinary planning. The journal publishes peer-reviewed research on fetal diagnosis, imaging, genetics, and the prenatal evaluation of conditions amenable to intervention, supporting the integration of diagnostic findings with maternal-fetal and surgical care across a range of congenital and inherited disorders.
Research published in this journal
12 peer-reviewed articles, ranked by relevance. Each links to its DOI.
The Additional Diagnostic Value of the Three-dimensional 3D ultrasound and Doppler angiography imaging in the prenatal diagnosis of left isomerism
A Trio Study Showing Novel Gene Mutation In LAMB3 Causing Junctional Epidermolysis Bullosa (Intermediate/ Severe)
Unusual Presentation Of Tracheoesophageal Fistula With Meconium Aspiration Syndrome In A Preterm Infant
Tay-Sachs Disease: From Molecular Characterization to Ethical Quandaries and the Possibility of Genetic Medicine
The Genetic Multiplicity- Multiple Endocrine Neoplasia type I
Understanding Inherited Bleeding Disorders: Genetic Mutations in Blood Coagulation Factors and Regulatory Proteins
Toward Better Care for Sickle Cell Disease in Nigeria: A Review of Challenges and Interventions
Fetal Abdominal Cystic Lesion: A Diagnostic Dilemma and Prognostic Challenge-Report of Two Cases of Mesentric Lymphangioma with Review of Literature
The Evolution of Fetal Surgery
Oral Ellis-Van Creveld Syndrome: A Brief Review of Literature and A Case Report
Factors Impacting Nutritional Status in Infants with Single Ventricle Physiology
How this research is being cited
The 12 articles above have been cited 6 times in the scholarly literature. Citation data via OpenAlex and Crossref, updated Jun 2026.
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2024 · medRxiv (Cold Spring Harbor Laboratory)
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B. Baghianimoghadam et al. · 2021 · Acta medica Lituanica
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Kotaiah Theruru et al. · 2021 ·
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2021 · Acta medica Lituanica
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W. E. Guindi et al. · 2021 · Integrative Gynecology and Obstetrics Journal
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2021 ·
A sample of recent works citing this journal's research on Prenatal Diagnosis, linking to each citing work.