Journal of Experimental and Clinical Toxicology

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Experimental and Clinical Toxicology-In vitro and in vivo toxicology-Laetitia Gonzalez


Vrije Universiteit Brussel,
Free University of Brussels.

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Laetitia Gonzalez


Pleinlaan 2,
1050 Brussels.

Research Interests:

In vitro and in vivo toxicology, genotoxicology, nanotoxicology, developmental toxicology modes of action, environmental mutagenesis


Since 2011 researcher at the Free University of Brussels (VUB) and visiting researcher at the Institute of Molecular Biology and Pathology at the National Research Council in Rome, Italy


  1. Biomonitoring of genotoxic effects for human exposure to nanomaterials: The challenge ahead..
  2. Tetraploid cells produced by absence of substrate adhesion during cytokinesis are limited in their proliferation and enter senescence after DNA replication.
  3. Towards a new paradigm in nano-genotoxicology: Facing complexity of nanomaterials cellular interactions and effects.
  4. Amorphous silica nanoparticles alter microtubule dynamics and cell migration.
  5. Assessing the carcinogenic potential of low-dose exposures to chemical mixtures in the environment: the challenge ahead.
  6. Causes of genome instability: the effect of low dose chemical exposures in modern society.
  7. Co-assessment of cell cycle and micronucleus frequencies demonstrates the influence of serum on the in vitro genotoxic response to amorphous monodisperse silica nanoparticles of varying sizes.
  8. Influence of serum on in situ proliferation and genotoxicity in A549 human lung cells exposed to nanomaterials.
  9. Letter to the Editor Regarding the Article by Wittmaack.
  10. Oxidative Stress Induced by Pure and Iron-Doped Amorphous Silica Nanoparticles in Subtoxic Conditions.