Platelet Aggregation

Platelet Aggregation is the process whereby platelets, a type of blood cell, stick together to form clumps or aggregates. It is an important process in the body that helps it to heal wounds and prevent bleeding. Platelet aggregation is necessary to initiate clotting and seal the wound. Abnormal platelet aggregation can lead to thrombosis, or blood clots, which can be dangerous if not managed correctly. Platelet aggregation can be measured in the laboratory using a variety of techniques including light transmission aggregometry, turbidimetry, and the Plateletworks assay. Knowing the platelet aggregation status helps in diagnosing, treating and monitoring of various diseases and conditions like thrombosis, coronary artery disease, stroke, and hypertension. Platelet aggregation assays are used to improve patient diagnosis as well as to assess the effectiveness of treatments like aspirin and other antiplatelet drugs.