Journal of Immunology and Geriatrics

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Immunology and Geriatrics-Construction and purification of human antibodies-Yuan Mao

China

Department of Oncology,
Nanjing Medical University,
Nanjing, China.

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Yuan Mao

Address:

Department of Hematology and Oncology,
Jiangsu Province Geriatric Hospital,
No.65 Jiangsu Road,
Nanjing, China.

Research Interests:

  • Construction and purification of human antibodies 
  • Proficient in operations of Immunology 
  • Molecular and genetic epidemiology

Biography:

Education:    

  • Ph.D. candidate in Oncology - Sep.2015-present, Department of Oncology, Nanjing Medical University, Nanjing, China
  • M.D. in Otolaryngology - Sep.2008-Jul.2011, Department of Otolaryngology, Head and Neck Oncology; Key Lab of Antibody Technique of Ministry of Health, Nanjing Medical University, Nanjing, China
  • B.S. in Clinical Medicine - Sep.2001-Jul.2006, Nanjing Medical University, Nanjing, China

Publications:

  1. Mao Y, Zhang DW, Wen J, et al. A novel LMP1 antibody synergizes with Mitomycin C to inhibit nasopharyngeal carcinoma growth in vivo through inducing apoptosis and downregulating vascular endothelial growth factor. Int J Mol Sci, 2012, 13: 2208-2218.
  2. Mao Y, Zhang DW, Zhu H, et al. LMP1 and LMP2A are potential prognostic markers of extranodal NK/T-cell lymphoma, nasal type (ENKTL). Diagn Pathol, 2012, 7: 178.
  3. Mao Y, Zhang DW, Lin H, et al. Alpha B-crystallin is a new prognostic marker for laryngeal squamous cell carcinoma. J Exp Clin Cancer Res, 2012, 31: 101.
  4. Mao Y, Lu MP, Lin H, et al. Prognostic Significance of EBV Latent Membrane Protein 1 Expression in Lymphomas: Evidence from 15 Studies. PLoS One, 2013, 8:e60313.  
  5. Mao Y, Wang J, Zhang M, et al. A neutralized human LMP1-IgG inhibits ENKTL growth by suppressing the JAK3/STAT3 signaling pathway. Oncotarget. 2016 Dec 20. doi: 10.18632/oncotarget.14032.
  6. Lin H, Mao Y, Zhang DW, et al. Selection and Characterization of Human Anti-MAGE-A1 scFv and Immunotoxin. Anti-cancer Agents in Medicinal Chemistry, 2013, 13:1259-1266. (co-first author)
  7. Zhang D, Mao Y, Xiong L, et al. Characterization of human Fab antibody fragments specific to LMP1 (HLEAFab) in nasopharyngeal carcinoma for potential molecular diagnosis and therapeutic applications. Oncol Lett, 2013, 5: 1694-1698. (co-first author)
  8. Zhang D, Mao Y, Cao Q, et al. Generation and characterization of a novel recombinant antibody against LMP1-TES1 of Epstein-Barr virus isolated by phage display. Viruses, 2013, 5:1131-1142. (co-first author)
  9. Zhang H, Mao Y, Zhang F, et al. The inhibitory effect of a new scFv/tP protein as siRNA delivery system to target hWAPL in cervical carcinoma. Mol Cell Biochem, 2014 Jun;391(1-2):77-84. (co-first author)
  10. Zhu H, Lu J, Mao Y, et al. Upregulated ZO-1 correlates with favorable survival of gastrointestinal stromal tumor. Med Oncol, 2013,30:631. (corresponding author)