Journal of Hereditary Diseases

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Hereditary Diseases-Biotechnology-Yonghui Li

China

  • General Secretary of Precision Medicine Society of Hematology, Chinese Research Hospital Association, Department of Hematology,
  • The General hospital of PLA, Beijing. Associated professor.

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Yonghui Li

Address:

Hematology, Chinese PLA General Hospital 28, Fuxing Road, Beijing,100853

Research Interests:

Biotechnology, Molecular Biology, Genetics, Structural Biology, Nanotechnology, Analytical Chemistry, Biochemistry, Nanobiochemistry, Chemical Biology, Electrochemistry.

Biography:

Publications:
  1. Li Y, Ning Q, Shi J, Chen Y, Jiang M, Gao L, Huang W, Jing Y, Huang S, Liu A, Hu Z, Liu D, Wang L, Nervi C, Dai Y, Zhang MQ, Yu L. A novel epigenetic AML1-ETO/THAP10/miR-383 mini-circuitry contributes to t(8;21) leukaemogenesis. EMBO Mol Med, 2017, 9(7):933-949.
  2. Liang Y, Zhou H, Yao Y, Deng A, Wang Z, Gao B, Zhou M, Cui Y, Wang L, Zhou L, Wang B, Wang L, Liu A, Qiu L, Qian K, Lu Y, Deng W, Zheng X, Han Z, Li Y,* Sun J. 12-O-tetradecanoylphorbol-13-acetate (TPA) increases murine intestinal crypt stem cell survival following radiation injury. Oncotarget, 2017, 8(28):45566-45576. 
  3. Fu L, Shi J, Liu A, Zhou L, Jiang M, Fu H, Xu K, Li D, Deng A, Zhang Q, Pang Y, Guo Y, Hu K, Zhou J, Wang Y, Huang W, Jing Y, Dou L, Wang L, Xu K, Ke X, Nervi C, Li Y,* Yu L. A minicircuitry of microRNA-9-1 and RUNX1-RUNX1T1 contributes to leukemogenesis in t(8;21) acute myeloid leukemia, Int J Cancer, 2016, 40(3):653-661.
  4. B Wang, Y Liu, L Wang, N Lv, Y Xu, Y Xu, X Wang, Z Xuan, Y Jing, H Li, X Jin, A Deng, L Wang, X Gao, L Dou, J Liang, C Chen, Y Li*, L Yu*. Mutational spectrum and risk stratification of intermediate-risk acute myeloid leukemia patients based on next-generation sequencing, Oncogarget, 2016, 7(22):32065-78. 
  5. Chen Z, Tan L, Wang S, Zhang Y, Li Y*. Sensitive colorimetric detection of K(I) using catalytically active gold nanoparticles triggered signal amplification. Biosens Bioelectron, 2016, 79:749-757.
  6. Li D, Wang L, Zhu H, Dou L, Liu D, Fu L, Ma C, Ma X, Yao Y, Zhou L, Wang Q, Wang L, Zhao Y, Jing Y, Wang L, Li Y*. Yu L. Efficacy of Allogeneic Hematopoietic Stem Cell Transplantation in Intermediate-Risk Acute Myeloid Leukemia Adult Patients in First Complete Remission: A Meta-Analysis of Prospective Studies. PLoS One. 2015 Jul 21;10(7):e0132620. 
  7. Wang BH, Li YH, Li Y. Genomics-based approach and prognostic stratification significance of gene mutations in intermediate-risk acute myeloid leukemia. Chin Med J, 2015, 128(17):2395-403.
  8. Fu L, Huang W, Jing Y, Jiang M, Zhao Y, Shi J, Huang S, Xue X, Zhang Q, Tang J, Dou L, Wang L, Nervi C, Li Y*, Yu L*. AML1/ETO triggers epigenetic activation of EGR1 inducing apoptosis in t(8;21) acute myeloid leukemia. FEBS J. 2014, 281:1123-31. 
  9. Yonghui Li, Li Gao, Xufeng Luo, Lili Wang, Xiaoning Gao, Wei Wang, Junzhong Sun, Liping Dou, Jingxin Li, Chengwang Xu, Lixin Wang, Minhang Zhou, Mengmeng Jiang, Jihao Zhou, Michael A. Caligiuri, Clara Nervi, Clara D. Bloomfield, Guido Marcucci, and Yu L. Epigenetic Silencing of microRNA-193a Contributes to Leukemogenesis in t(8;21) Acute Myeloid Leukemia by Activating the PTEN/PI3K Signal Pathway. Blood, 2013,121(3):499-509. 
  10. Leong DJ*, Li YH*, Gu XI*, Sun L, Zhou Z, Nasser P, Laudier DM, Iqbal J, Majeska RJ, Schaffler MB, Goldring MB, Cardoso L, Zaidi M, Sun HB. Physiological loading of joints prevents cartilage degradation through CITED2. FASEB J, 2011, 25(1):182-91. 
  11. Wang BH, Li YH, Li Y. Genomics-based approach and prognostic stratification significance of gene mutations in intermediate-risk acute myeloid leukemia. Chin Med J, 2015, 128(17):2395-403.
  12. Fu L, Huang W, Jing Y, Jiang M, Zhao Y, Shi J, Huang S, Xue X, Zhang Q, Tang J, Dou L, Wang L, Nervi C, Li Y*, Yu L*. AML1/ETO triggers epigenetic activation of EGR1 inducing apoptosis in t(8;21) acute myeloid leukemia. FEBS J. 2014, 281:1123-31.(IF:4.26,Co-responding author).