Name: Xiang Zhang

Country: United States


University of Texas Health,
Science Center at Houston.

Email: Send an Email


1941 East Road,
TX 77054,
United States.

Research Interests:

  • One set of his studies focuses on oxidative stress in schizophrenia. An ancillary theme is research on the association of free radical metabolism and the pathophysiology of tardive dyskinesia (TD), a movement disorder commonly occurs in patients treated chronically with antipsychotic drugs. 
  • Dr Zhang's interest in this area has led to studies that underlined the importance of the antioxidant in the outcome of schizophrenia, as well as TD treatment.
  • A second set of studies lie in the role of viruses and other infectious agents, together with immune dysfunction as possible causes of schizophrenia.
  • A third research interest focuses on genetics and pharmacogenetics of psychiatric illness, mainly schizophrenia and antipsychotic-induced side effects, such as tardive dyskinesia, weight gain/obesity and diabetes.
  • A fourth set of studies utilizes a translational approach to understand addiction vulnerability in patients with serious mental disorders mainly schizophrenia. His main focus has been on tobacco addiction co-morbidity.


Current address:  Department of Psychiatry and Behavioral Sciences, The University of Texas Health Science Center at Houston,  1941 East Road, Houston, TX 77054, USA, Tel: 713-791-1414 ext. 5824; 832-472-8148 (cell), Fax:713-794-7938, E-mail: [email protected], Place of Birth: Guoyang, Anhui Province, CHINA, 

Ph.D.  Psychopharmacology, Institute of Mental Health, Peking University School of Medicine, 
           Beijing, CHINA.   Sep 1995-July 1998
M.S.   Psychopharmacology, Institute of Mental Health, Peking University School of Medicine, 
            Beijing, CHINA.   Sep 1992-July 1995

M.D.    Anhui Medical University, HeFei, Anhui, CHINA.   Sep 1984- July 1989

July 2009-Present      Associate Professor, Department of Psychiatry and Behavioral Sciences,
                                      Baylor College of Medicine 
July 2006-June 2009  Assistant Professor, Department of Psychiatry and Behavioral Sciences,
                                      Baylor College of Medicine 
July 2003-June 2006   Associate Research Scientist, Department of Psychiatry, 
                                      Yale University School of Medicine, Connecticut, USA
Aug 2000-June 2003   Postdoctoral Fellow, Department of Psychiatry, 
                                       Yale University School of Medicine, Connecticut, USA
Aug 1999-July 2000    Postdoctoral Fellow, Center for Molecular and Behavioral Neuroscience 
                                       Rutgers University, New Jersey, USA  
Aug 1998-July 1999    Research Fellow, Institute of Mental Health, 
                                        Peking University School of Medicine, Beijing, China  
Aug 1994-July 1998    Attending Psychiatrist, Beijing Hui-Long-Guan Psychiatric Hospital,   
                                        Beijing, China 
Aug 1989-July 1994   Resident in Psychiatry, Beijing Hui-Long-Guan Psychiatric Hospital,  
                                        Beijing, China     

Academic Review Experience:

National Grant Reviewer:  

The United States – Israel Binational Science Foundation (BSF)                            2012 

International Grant Reviewer:                                 
National Program on Key Basic Research Project of China                                     2013
National Program on Key Basic Research Project of China                                     2012
Changjiang Scholars Programme of China                                                               2012   
Neurosciences and Mental Health Board, UK                             2010
National Program on Key Basic Research Project of China                                     2010
Changjiang Scholars Programme of China                                                               2010   
Member of the Grant Review Board, Food and Health Bureau, Hong Kong           2012

Editorial Board:
   Plos ONE                                                                                                                    2010-present
   Progress in Neuro-Psychopharmacology & Biological Psychiatry                            2009-present   
   Gust editor, Progress in Neuro-Psychopharmacology & Biological Psychiatry        2012
Neuropsychopharmacology Open Journal                                                                 2009-2012  
Journal of Addiction & Prevention                                                                            2013-present 
Hindawi ISRN Psychiatry                                                                                          2013-present
Psychology and Behavioral Sciences                                                                         2013-present


Journal Reviewer (Ad hoc):                                             2006-present
         Acta Pharmacologica Sinica, ACTA Psychiatric Scandinavica, Addiction, Addictive biology,  AIDS and Behavior, American Journal of Drug Addiction, American Journal of Drug and Alcohol Abuse, American Journal of Medical Genetics Part B,  American Journal of Psychiatry, Antioxidants and Redox Signaling, Archives of General Psychiatry, Behavioral Psychopharmacology, Biological Psychiatry, Bipolar Disorders, Brain Research, Cytokines, European Journal of Neuropsychopharmacology, Human Psychopharmacology, Indian Journal of Psychiatry, Journal of Clinical Psychiatry, Journal of Nutritional Biochemistry,  Journal of Psychiatric Research, Journal of Psychopharmacology, Journal of Public Health, Journal of Traumatic Stress, Molecular Psychiatry, Neuropsychopharmacology, Neuroscience Letters, Pharmacology, Biochemistry and Behavior,  Plos One, Progress in Neuro-Psychopharmacology & Biological Psychiatry, Psychiatry Research, Psychopharmacology, Schizophrenia Bulletin, Schizophrenia Research, The Lancet. 







Current Support:
National Natural Science Foundation of China (81371477)                                          2014-2017
  “Tropisetron for cognitive function and P50 in chronic schizophrenia” 
 Role: Principal Investigator  

2013 NARSAD Independent Investigator Grant (#20314)                                              2013-2015
   Ã¢â‚¬Å“Tropisetron for clinical symptom and cognitive biomarkers in schizophrenia: 
association with alpha 7 nicotinic receptor gene polymorphisms” 
Role: Principal Investigator  

Beijing Municipal Natural Science Foundation (#7132063)                                            2013-2016  
         Ã¢â‚¬Å“The pharmacogenetic mechanisms of antipsychotic-induced weight gain and obesity”           Role: Principal Investigator

National Institute of Drug Abuse, 7P50DA018197                            2009-2014
“Stimulant pharmacotherapy: Noradrenergic Targets”
    Role: Core-PI 

  • Dr Zhang has a broad background in psychiatry, with specific training and expertise in clinical psychopharmacology and pharmacogenetics in schizophrenia. 
  • As PI or co-Investigator on several previous Stanley Medical Research Institute foundation NARSAD and NIH-funded grants, Dr Zhang laid the groundwork for the proposed research by collecting large samples from the patients with schizophrenia who had been treated with atypical and typical antipsychotics, and by establishing a large research net all over China, in which 8 large psychiatric hospitals have participated for collaborative efforts, with more than 6,000 inpatients. 
  • In addition, Dr Zhang successfully administered the projects (e.g. staffing, research protections, budget), collaborated with other researchers, and produced many peer reviewed publications from each project. 
  • Up to date, Dr Zhang has published more than 150 papers in the international peer-review journals. 
  • In summary, Dr Zhang has a demonstrated record of successful and productive research projects in an area of clinical psychopharmacology and pharmacogenetic in schizophenia.