Name: Sudha Chaturvedi

Country: United States

Affiliation:

Assistant Professor, Biomedical Sciences, School of Public Health, University at Albany.

Phone no: (518) 474-7563

Email: Send an Email


Address:

New York State Department of Health Albany, New York

Research Interests:

  • Fungal pathogenesis, protein transport, & secretion mechanisms. 
  • The focus of my laboratory is to understand fungal pathogenesis with special emphasis on Cryptococcus species (Cs). 
  • Cs, encapsulated yeast, causes infections in both healthy and immunocompromised individuals. 
  • Central to this investigation is an understanding of what gene products are required and expressed during infection and how this expression changes over time (from initial colonization to causation of disease) and space (in different cells or tissues within the host). 
  • We thus endeavor to understand, what selective pressures are acting on the pathogen in each microenvironment, what fungal factors are responsible for the host damage, and how the immune system is evaded.
  • Another focus of my laboratory is to understand the molecular mechanisms underlying the non-classical release of oxidative proteins. 
  • Major aim of this investigation is to define how non-classically exported proteins pass through the cell membrane and cell wall, and which membrane and cell wall proteins facilitate these processes.

Biography:

Publications:

  1. Mycobiome of the Bat White Nose Syndrome (WNS) Affected Caves and Mines reveals High Diversity of Fungi and Local Adaptation by the Fungal Pathogen Pseudogymnoascus (Geomyces) destructans.
  2. Draft Genome Sequences of Human Pathogenic Fungus Geomyces pannorum Sensu Lato and Bat White Nose Syndrome Pathogen Geomyces (Pseudogymnoascus) destructans.
  3. Clonal Genotype of Geomyces destructans among Bats with White Nose Syndrome, New York, USA.
  4. Editorial: What is in a Name? A Proposal to Use Geomycosis Instead of White Nose Syndrome (WNS) to Describe Bat Infection Caused by Geomyces Destructans.
  5. Extracellular Fibrils of Pathogenic Yeast Cryptococcus gattii Are Important for Ecological Niche, Murine Virulence and Human Neutrophil Interactions.
  6. Morphological and Molecular Characterizations of Psychrophilic Fungus Geomyces destructans from New York Bats with White Nose Syndrome (WNS).
  7. Efficacy of Immunoprecipitation Methods for Rapid Serodiagnosis of Allergic Bronchopulmonary Aspergillosis: Die Aussagekraft von Immunpräzipitationstechniken für die Seroschnelldiagnose der allergisch‐bronchopulmonalen Aspergillose.
  8. Characterization of Cryptococcus neoformans variety gattii SOD2 reveals distinct roles of the two superoxide dismutases in fungal biology and virulence.
  9. Characterization of Cu,Zn superoxide dismutase (SOD1) gene knock-out mutant of Cryptococcus neoformans var. gattii: Role in biology and virulence.
  10. Direct PCR of Cryptococcus neoformans MATα andMAT a Pheromones To Determine Mating Type, Ploidy, and Variety: a Tool for Epidemiological and Molecular Pathogenesis Studies.