Name: Rosario Barone

Country: Italy

Affiliation:

University of Palermo

Email: Send an Email


Address:

University of Palermo, via del vespro 129 - 90127 Palermo

Research Interests:

  • Structural modifications of the patellar tendon of adult rat after different training protocols.
  • Study of the effects of conjugated linoleic acid (CLA) and nandrolone decanoate (ND) in vitro (Leydig R2C cells) and in vivo (trained Balb / c mouse) in skeletal muscle homeostasis, testis, heart and liver.
  • Expression levels of Hsp60 protein in the skeletal muscle of sedentary and trained mouse and correlation between the overexpression of the same protein in a cell line (C2C12 myoblasts) and the expression of the mitochondrial biogenesis PGC1 alpha.
  • Effects of different training protocols on a cachectic mouse model.

Biography:

Publications

  1. HSP60 is a Ubiquitous Player in the Physiological and Pathogenic Interactions between the Chaperoning and the Immune Systems
  2. P 177. αB-crystallin activation in cardiac muscle by acute exercise mirrors the sHSP kinetic in oxidative skeletal muscle fibers: animal and cellular study
  3. The dissociation of the Hsp60/pro-Caspase-3 complex by bis(pyridyl)oxadiazole copper complex (CubipyOXA) leads to cell death in NCI-H292 cancer cells
  4. Nandrolone decanoate interferes with testosterone biosynthesis altering blood-testis barrier components
  5. Doxorubicin anti-tumor mechanisms include Hsp60 post-translational modifications leading to the Hsp60/p53 complex dissociation and instauration of replicative senescence
  6. Exercise-Induced Activation and Translocation of αB-Crystallin in Skeletal Muscle Depends upon Fiber Type and Oxidative Stress
  7. Histone macroH2A1.2 promotes metabolic health and leanness by inhibiting adipogenesis
  8. Mild Aerobic Exercise Training Hardly Affects the Diaphragm of mdx Mice
  9. Effects of Conjugated Linoleic Acid Associated with Endurance Exercise on Muscle Fibres and Peroxisome Proliferator-Activated Receptor γ Coactivator 1 α Isoforms: CLA and exercise on IIx muscle fibres and PGC1α
  10. Quantitative patterns of Hsps in tubular adenoma compared with normal and tumor tissues reveal the value of Hsp10 and Hsp60 in early diagnosis of large bowel cancer