Name: Maria Isabel Veiga

Country: Portugal

Affiliation:

Life and Health Sciences Research Institute (ICVS), School of Medicine and ICVS/3B's-PT Government Associate Laboratory, University of Minho, Portugal.

Email: Send an Email


Address:

Life and Health Sciences Research Institute (ICVS), 
Universidade do Minho Campus de Gualtar 4710-057 Braga, 
Portugal.

 

Research Interests:

  • Malaria (plasmodium) 
  • Drug resistance 
  • Drug transporters

Biography:

  • Overall, published 23 papers evidencing a unique and translational approach tackling how the malaria parasite escapes the action of a therapeutic drug. 
  • Her work also contributes to reinforce the concept of malaria drug resistance as a multi-factorial and complex phenomenon that not only relates to the parasite’s handling of the incoming drug, but also concomitant responses of its basic physiology and the human host factors. 
  • In recognition of her work, she was awarded in 2017 by L'Oréal Portugal with an Honor Medals for Women in Science. International impact of her research can be accessed by the over 650 citations with 98 co-authors rendered into a strong collaborative network translated into funds and students overseas to proceed with post-graduation at the ICVS, UMinho. https://orcid.org/0000-0002-2205-8102 http://icvs.uminho.pt/about-icvs/people/mariaveiga.

Publications:

  1. Title: Dosage of single low-dose primaquine to stop malaria transmission.
  2. Title: Plasmodium falciparum Plasmepsin 2 Duplications, West Africa
  3. Title: Hexahydroquinolines are antimalarial candidates with potent blood-stage and transmission-blocking activity.
  4.  Title: Globally prevalent PfMDR1 mutations modulate Plasmodium falciparum susceptibility to artemisinin-based combination therapies.
  5. Title: Complex polymorphisms in the Plasmodium falciparum Multidrug Resistance Protein 2 gene and its contribution to antimalarial response.
  6. Title: Single nucleotide polymorphisms in Plasmodium falciparum V type H+ pyrophosphatase gene (pfvp2) and their associations with pfcrt and pfmdr1 polymorphisms
  7. Title: pfmdr1 amplification is related to increased Plasmodium falciparum in vitro sensitivity to the bisquinoline piperaquine
  8. Title: Drug resistance associated genetic polymorphisms in Plasmodium falciparum and Plasmodium vivax collected in Honduras, Central America
  9. Title: Novel polymorphisms in plasmodium falciparum ABC transporter genes are associated with major ACT Antimalarial drug resistance
  10. Title: PfMDR1: Mechanisms of transport modulation by functional polymorphisms.