Journal of Psychophysiology Practice and Research

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Psychophysiology Practice and Research-Animal models of neuropsychiatric and neurologic disorders with an greater emphasis on schizophrenia-Jeffrey Eells

United States

Ph.D., Southern Illinois University, Postdoctoral Fellow, University of North Carolina at Chapel Hill; National Institute for Diabetes and Digestive and Kidney Diseases

252-744-2819

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Jeffrey Eells

Address:

Brody School of Medicine 600 Moye Blvd Mail Stop 620 East Carolina University Greenville, NC 27834-4354

Research Interests:

Animal models of neuropsychiatric and neurologic disorders with an greater emphasis on schizophrenia, addiction, and Parkinson's disease

Biography:

Publications:

  1. Eells, J.B., J.A. Misler, and V.M. Nikodem. 2006. Reduced tyrosine hydroxylase and GTP cyclohydrolase mRNA expression, tyrosine hydroxylase activity, and associated neurochemical alterasions in Nurr1-null heterozygous mice. Brain Res. Bull. 70: 186-195. PMID: 16782508.
  2. Gil, M., C. McKinney, M.K. Lee, J.B. Eells, M.A. Phyillaier, and V.M. Nikodem. 2007. Regulation of GTP-cyclohydrolase 1 gene expression by orphan receptor Nurr1 in cell culture and in vivo. J. Neurochem. 101: 142-150. PMID: 17394463.
  3. Moore, T.M., T. Brown, M. Cade, and J.B. Eells. 2008. Alterations in amphetamine-stimulated dopamine overflow due to the Nurr1-null heterozygous genotype and postweaning isolation. Synpase. 62: 764-774. PMID: 18655117.
  4. Eells, J.B. and T.W. Brown. 2009. Repeated developmental exposure to chlorpyrifos and methyl parathion causes persistent alterations in nicotinic acetylcholine subunit mRNA expression with chlorpyrifos altering dopamine metabolite levels. Neurotoxiol. Teratol. 31: 90-103. PMID: 18977431.
  5. Scott, V.L., L.A. Shack, J.B. Eells, P.L. Ryan, J.R. Donaldson, and K.S. Coats. 2011. Immunomodulator expression in trophoblasts from the feline immunodeficiency virus (FIV)-infected cat. Virol. J. 8: 336. PMID: 21729293.
  6. Eells, J.B., J. Wilcots, S. Sisk, and S.X. Guo-Ross. 2011. NR4A gene expression is dynamically regulated in the ventral tegmental area dopamine neurons and is related to expression of dopamine neurotransmission genes. J. Mol. Neurosci. 46: 545-553. PMID: 21932041.
  7. Kummari, E., S.X. Guo-Ross, and J.B. Eells. 2015. Laser capture microdissection – a demonstration of the isolation of individual dopamine neurons and the entire ventral tegmental area. J. Vis. Exp. 96: e52336. PMID: 25742438.
  8. Eells, J.B., A. Varela-Stokes, S.X. Guo-Ross, E. Kummari, H.M. Smith, E. Cox, and D.S. Lindsay. 2015. Chronic toxoplasma gondii in Nurr1-null heterozygous mice exacerbates elevated open field activity. PLoS ONE. 10: e0119280. PMID: 25855987.
  9. Yang, E.J., J.V. Stokes, E. Kummari, J. Eells, and B.L. Kaplan. 2016. Immunomodulation by subchronic low dose 2,3,7,8-Tetrachlorodibenzo-p-dioxin in experimental autoimmune encephalomyelitis in the absence of pertussis toxin. Toxicol. Sci. 151: 35-43. PMID: 26822306.
  10. Carr, R.L., N.H. Armstrong, A.T. Buchanan, J.B. Eells, A.N. Mohammed, M.K. Ross, and C.A. Nail. 2017. Decreased anxiety in juvenile rats following exposure to low levels of chlorpyrifos during development. NeuroTox. 59: 183-190. PMID: 26642910.