Name: Jean MARIANI

Country: France


University P.&M. Curie Sorbonne University

Phone no: (33 1) 44 27 32 40/ 32 36, 33 06 73 57 31 36

Email: Send an Email


Ph.D. UMR 8256 B2A Biological Adaptation and Ageing Team Brain Development,

Repair and Aging (BDRA),

Direcor of Longevity Institute Boite 14,

University P. and M. Curie, 9 quai St Bernard, 75005, Paris, FRANCRE.

Research Interests:

neuroinflammation and brain aging nuclear receptors role in inflammation and control of cytokines aging and inflammaging clincla research on aging



  1. Normal adult climbing fiber monoinnervation of cerebellar Purkinje cells in mice lacking MHC class I molecules.
  2. Beta adrenergic induced K+ current Xenopus oocytes role of cAMP inhibition by muscarinic agents.
  3. The Oxygen Paradox, the French Paradox, and age-related diseases.
  4. RORα Coordinates Thalamic and Cortical Maturation to Instruct Barrel Cortex Development.
  5. Acute Stress Affects the Expression of Hippocampal Mu Oscillations in an Age-Dependent Manner.
  6. Relationship between sleep parameters, insulin resistance and age-adjusted insulin like growth factor-1 score in non diabetic older patients.
  7. Étude FALL-Aging-SLEEP : insomnie, chutes et sarcopénie chez les patients gériatriques.
  8. Étude Fall-Aging-Sleep : Apnées du sommeil, chutes et sarcopénie chez les patients gériatriques.
  9. NMDA Receptor Contribution to the Climbing Fiber Response in the Adult Mouse Purkinje Cell.
  10. Defining the brain circuits involved in psychiatric disorders: IMI-NEWMEDS.
  11. Deletion of the GluRδ2 Receptor in the Hotfoot Mouse Mutant Causes Granule Cell Loss, Delayed Purkinje Cell Death, and Reductions in Purkinje Cell Dendritic Tree Area.
  12. Underperception of Naps in Older Adults Referred for a Sleep Assessment: An Insomnia Trait and a Cognitive Problem?
  13. Interleukin-10 Production in Response to Amyloid-β Differs between Slow and Fast Decliners in Patients with Alzheimer’s Disease.
  14. Leukocyte Telomere Length in Alzheimer’s Disease Patients with a Different Rate of Progression.
  15. The retinoid-related orphan receptor alpha is essential for the end-stage effector phase of experimental epidermolysis bullosa acquisita.
  16. Hypertension Accelerates the Progression of Alzheimer-Like Pathology in a Mouse Model of the Disease.