Catholic University of Louvain
Institute for Experimental and Clinical Research
Avenue Mounier 52, box. B1.52.02
Tissue engineering, fertility, reproduction, biomaterials.
- I hold a bachelor’s degree in Veterinary Medicine and a PhD in animal reproduction.
- For the past 20 years I have worked with follicles from a whole range of mammalian species.
- Initially, I focused on domestic animals, developing projects to safeguard native breeds from Brazil and Italy through the establishment of cryopreservation procedures for isolated follicles and ovarian tissue.
- Since 2007 I have been working with human preantral follicles.
- My major goal is to create a transplantable artificial ovary to restore fertility in cancer patients.
- Additionally, I conduct studies on ovarian tissue characterization, cryopreservation and xenotransplantation.
- Reimplantation of cryopreserved ovarian tissue from patients with acute lymphoblastic leukemia is potentially unsafe.
- Survival of human pre-antral follicles after cryopreservation of ovarian tissue, follicular isolation and in vitro culture in a calcium alginate matrix.
- Vitrification as an alternative means of cryopreserving ovarian tissue.
- IVF outcome in patients with orthotopically transplanted ovarian tissue.
- Study of preantral follicle population in situ and after mechanical isolation from caprine ovaries at different reproductive stages.
- Effect of the interval of serial sections of ovarian tissue in the tissue chopper on the number of isolated caprine preantral follicles.
- Vitrification and xenografting of human ovarian tissue.
- Cryopreservation of caprine ovarian tissue using dimethylsulphoxide and propanediol.
- A review of 15 years of ovarian tissue bank activities.
- Transplantation of an alginate–matrigel matrix containing isolated ovarian cells: first step in developing a biodegradable scaffold to transplant isolated preantral follicles and ovarian cells.