Name: Bianca Marchetti

Country: Italy

Affiliation:

University of Catania, Department of Clinical and Molecular Biomedicine, Catania

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Address:

University of Catania, Department of Clinical and Molecular Biomedicine, Catania.

Research Interests:

Medicine and Life Scinces.

Biography:

Publications:

  1. microRNAs in Parkinson’s Disease: From Pathogenesis to Novel Diagnostic and Therapeutic Approaches.
  2. Wnt3a promotes pro-angiogenic features in macrophages in vitro : Implications for stroke pathology.
  3. Nigrostriatal degeneration dictates a top-down genetic program for neuroplasticity and neurorepair: Focus on the hippocampus and Wnt/GSK-3β/β-catenin signaling cascade.
  4. Wnt/β-Catenin Signaling Is Required to Rescue Midbrain Dopaminergic Progenitors and Promote Neurorepair in Ageing Mouse Model of Parkinson's Disease.
  5. The role of the immune system in central nervous system plasticity after acute injury.
  6. Targeting Wnt signaling at the neuroimmune interface for dopaminergic neuroprotection/repair in Parkinson's disease.
  7. Uncovering novel actors in astrocyte-neuron crosstalk in Parkinson's disease: The Wnt/β-catenin signaling cascade as the common final pathway for neuroprotection and self-repair.
  8. Reactive Astrocytes Are Key Players in Nigrostriatal Dopaminergic Neurorepair in the Mptp Mouse Model of Parkinson’s Disease: Focus on Endogenous Neurorestoration.
  9. Aging-Induced Nrf2-ARE Pathway Disruption in the Subventricular Zone Drives Neurogenic Impairment in Parkinsonian Mice via PI3K-Wnt/ -Catenin Dysregulation.
  10. Plasticity of Subventricular Zone Neuroprogenitors in MPTP (1-Methyl-4-Phenyl-1,2,3,6-Tetrahydropyridine) Mouse Model of Parkinson's Disease Involves Cross Talk between Inflammatory and Wnt/ -Catenin Signaling Pathways: Functional Consequences for Neuroprotection and Repair.
  11. Switching the Microglial Harmful Phenotype Promotes Lifelong Restoration of Subtantia Nigra Dopaminergic Neurons from Inflammatory Neurodegeneration in Aged Mice.
  12. A Wnt1 Regulated Frizzled-1/beta-Catenin Signaling Pathway as a Candidate Regulatory Circuit Controlling Mesencephalic Dopaminergic Neuron-Astrocyte Crosstalk : Therapeutical Relevance for Neuron Survival and Neuroprotection.

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