Open Source Drug Discovery

Open Source Drug Discovery (OSDD) is an innovative approach to tackle major global health challenges. It uses cutting-edge technology and collaborative agreements to enable researchers from academia, industry and other related communities to develop new medicines and treatments for previously neglected diseases. With the help of data sharing and open collaboration, the OSDD model allows drug discovery to move faster and more cost-effectively than traditional models. The application of Open Source Drug Discovery has enabled researchers to identify novel compounds and repurpose existing drugs for diseases such as tuberculosis, malaria, and neglected tropical diseases. Additionally, the highly collaborative nature of OSDD also fosters the development of novel treatments by bringing together multiple stakeholders and disciplines. Open Source Drug Discovery is an important tool to accelerate the development of treatments for neglected diseases and to improve global public health.

← Journal of Drug Resistant Pathogen Research

Related Articles

72 article(s) found
Evaluation of Direct Cost of Adverse Drug Reactions to Highly Active Antiretroviral Therapy in Indian Human Immunodeficiency Virus Positive Patients
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When and How Should we be Measuring Adherence to Antiretroviral Therapy in Resource-Limited Settings?
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Pattern of Use of Highly Active Antiretroviral Therapy Regimens and Pattern of Occurrence of Adverse Drug Reactions in an Indian Human Immunodeficiency Virus Positive Patients
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Bioinformatic Resources for Diabetic Nephropathy
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Evaluation of SterculiaUrens Gum as Novel Carrier for Oral Colon Targeted Drug Delivery System
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Discovery and Quantification in Mass Spectrometry-Based Proteomics
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Variation in Haemoglobin Reference Ranges and Implications for Use of Health Service Resource in the Republic of Ireland and the UK
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Current Status of Nonsteroidal Anti-Inflammatory Drugs in Colorectal Cancer Prevention
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Influence of Education Sources on Osteoporosis Knowledge and Calcium Intake in Adult Women: A cross sectional Study
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A Solitary Necrotic Lesion in A Man with Acute Myeloid Leukemia and neutropenia
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Proximate, Mineral and Antinutrient Compositions of Natural Cocoa Cake, Cocoa Liquor and Alkalized Cocoa Powders Sourced in Nigeria
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Influence of Light Source and Photopolymerization Distance on Composite Resin Microhardness
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Composite Photopolymerization: Temperature Increase According to Light Source and Dentin Thickness
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Synthesis and Assessment of a New Tetrahydrogeraniol Derivative as Penetration Enhancer for Transdermal Drug Delivery
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A Successful Vancomycin Treatment of Multidrug-Resistant MRSA-Associated Canine Pyoderma
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Anterior Open Bite Closure Using Ortodontic Mini-Implants
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Trends and inducing factors for illicit drug use in Grenada: Epoch 2001 – 2009.
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Immune Thrombocytopenia after Allogeneic Stem Cell Transplantation: Case Report and Brief Overview of Treatment Strategies
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Human Umbilical Cord-Derived Mesenchymal Stem Cells as a Source of Odontoblasts: a GMP-compliant Approach
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Sub-Types and Treatment Outcomes of adolescent and Adult Non-Hodgkin Lymphomas in a Resource Poor Setting
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Hospital Episodes Due to Antidepressant Overdose: An Under-Utilised Source of Pharmacovigilance Data
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Novel N-Pyrrolylcarboxylic Acid Derivative as a Potential New Analgesic and Anti-Inflammatory Drug
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Regulation of Expression of Reactive Oxygen Intermediates During Plasmodium Infection to Reduce Immunopathology Provides a Possible Antioxidant Adjuvant to Enhance Anti-Malarial Drug Therapy
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Profile of Similarity of Electron Withdrawing Structure Towards Analgesic-Anti-Inflammatory Activity of The Novel Isatin Analogue: Design and Implementation of Phase I Drug Discovery
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Sulfonamides: Historical Discovery Development (Structure-Activity Relationship Notes)
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Genetic Diversity of Large Japanese Field Mouse Apodemus speciosus Populations and Identification of their Food Plant Resources using DNA Barcoding in an Industrial Green Space
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Evaluation of Bacterial Population in the Saliva of Drug Addicts
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Drug Design Progress of In silico, In vitro and In vivo Researches
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Drug Abuse among Street Children
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The Pineal Hypothesis for Drug Dependence
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Why New Drugs, Treatments, and Medical Devices Still Needs to be Tested Clinically Before Making it Available in the Market?
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Successful Cascade of Care and Cure HCV in 5382 Drugs Users: How Increase HCV Treatment by Outreach Care, Since Screening to Treatment
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Resource Management Domains of Kharif and Rabi Season Fallows in Central Plateau Region of India: A Strategy for Accelerated Agricultural Development
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Forest Fragmentation Shapes Resource Partitioning for Endemic Pollinators (Hymenoptera: Meliponini)
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Characterization of rpoB Gene Mutations Associated with Rifampicin Resistance in Multidrug Resistant Tuberculosis Patients Co-infected with HIV from Southern India.
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Outcome Assessment of Open Foot Injuries in A Teaching Hospital in Ghana
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Possibility to Influence Treatment of Open Tibial Fracture by Negative Pressure Wound Therapy
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Open or Closed?
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Arbuscular Mycorrhizal Biofertilizers Sources in the Potato (Solanum Tuberosum) Plant show Interactions with Cultivars on Yield and Litter-bags Spectral Features
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Evaluation of cardiorespiratory parameters in dogs undergoing laparoscopic versus open gonadectomy with spontaneous ventilation anaesthesia: a pilot study
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Distribution Spread and Environmental Risk Status of Pb, Cd And Cr in Soils of an Open-Air Waste Dumpsite along Tombia/Amassoma Road in Yenagoa Metropolis
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Laboratory Tests Used in the Diagnosis of Immune Thrombocytopenia and General Treatment Approaches
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Use of Microfluidic Assays to Develop Reliable and Economic Nucleic Acid Application Technologies, Employing MicroRNAs for the Diagnostic Screening of Colon Cancer in Human Stool in Low-Resource Settings
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Biomedical Infophysical Models of Filtering Ghost Airflows by Wearing Masks and Maintaining Social Distancing to Prevent COVID-19 and Reopen All Systems after Shutdowns (Lockdowns)
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The Reopening of Schools and Adoption of Universal Wearing of Face Masks in Anticipation of Sustained Transmission or the Second Wave of COVID-19 with the Influenza Virus
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Lipid Assemblies as Tools for Drug Delivery
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Animals in the COVID-19 Era: Between Being a source, Victims, or Maybe our Hope to Overcome it!
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Assessment of Self Medication Practice and Drugs Storage Among South Sudanese Community in Addis Ababa, Ethiopia
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Community Based Study of Rural, Tribal Women Seeking Induced Abortions in a Extremely Low Resource Region
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Use of Microfluidic Assays to Develop Reliable and Economic Nucleic Acid Application Technologies, Employing MicroRNAs for the Diagnostic Screening of Colon Cancer in Human Stool in Low-Resource Settings
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The Feasibility of Enzyme Immunoassay Tests in the Absence of a Conventional Source of Electricity
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Digital Planning for Mini-Implant Supported Palatal Expander in Open-Bite Treatment
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The Multi Sectorial Approach to COVID-19 Pandemic in Limited-Resource Settings: Discussing Rwandan Experience
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Sub-Xiphoid Abscess and Sinus after Open Heart Surgery
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CERN Large Hadron Collider (LHC) Radiation Source for Magnetic Resonance Biospectroscopy in Metabolic and Molecular Imaging and Diagnosis of Cancer
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A Review on Drug Design by the Application of Computer
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Risk Management: Emerging critical issues during the hospital administration of drug therapy
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CalliphoraRomantis: Discovery of A New Species in The Field of Forensic Entomology
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Can Vitamin D Positively Impact Sarcopenia Severity Among Older Adults with Hand Osteoarthritis: A Review of the Evidence
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Effect of Protein and Energy-Dense Nutritional Supplement with Immunonutrients on Cachexia in Cancer Patients: An Open-Label, Single-Arm Study Among Indian Patients
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Hybrid Limited Shoulder Surgical Management (HLSSM) Sayed Issa's Hybrid Shoulder Arthroscopic-Open Surgical Management
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A case of delayed allergy after cyanoacrylate closure of varicose veins, diagnosed by drug-induced lymphocyte stimulation test
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Effect of Ultra-Processed Foods Consumption on Sleep Disturbances Among Brazilian Adults’ Population: A Propensity Score Matching Approach
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Human Immunodeficiency Virus Drug Resistance (HIVDR) and Baseline Characteristics among Antiretroviral Therapy (ART) experienced Children and Adolescents under the care of Chidamoyo Christian Hospital in Hurungwe, Zimbabwe
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Spirometric profile of people living with HIV on antiretroviral drugs in Abidjan
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The Application of Immunoglobulins Immune Response in the Discovery and Development of Safe Therapeutic Agents: A Review Article
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Disciplined Open-Air Exercise to Decelerate Aging: Toward Ecstatic Pains
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Measuring Quality Change in the Market for Anti-Ulcer Drugs
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Call to Action: The Need for Adverse Drug Event (ADE) Standardization and Codification Through Improved ADE Definitions, Documentation and Mapping, as well as More Refined Medication Definitions
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Water Quality Analysis on Public and Household Water Sources – A Case Study of Sunyani-West District, Fiapre
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Toxicology and Drug Safety Issues: A Review Article
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Characterization of People Receiving 2-Drug Regimens (2DR) for HIV Management in Italy
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