Somatic Mutation

Somatic mutation is a genetic change that takes place in the cells of an organism, excluding the reproductive cells (sperm and egg cells). These changes may be inherited by the offspring, but they occur in the cells which make up the body, impacting the phenotype of an individual. Somatic mutations are an important factor in the development of many diseases, such as cancer, and their study can give us insights into the formation and progression of these diseases. They also play an important role in a variety of medical treatments, such as gene therapy, where somatic mutations can be used to correct genetic defects. Furthermore, somatic mutations are a source of genetic variability, which helps promote evolutionary adaptations.

← Journal of DNA And RNA Research

Related Articles

19 article(s) found

Branch Retinal Vein Occlusion in Factor V Leiden Mutation

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Skeletal Muscle Calcium Channel Mutation R528G: Enhanced Channel Inactivation and Omega-Current at Hyperpolarization Contribute to Hypokalemic Periodic Paralysis.

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Childhood Somatic Complaints: Relationships with Child Emotional Functioning and Parental Factors

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The Identification of Somatic Mutations in Interferon-G Signal Molecules in Human Uterine Leiomyosarcoma

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Recurrent branch retinal arterial occlusions associated with plasminogen activator inhibitor-1 mutation

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Melanoma of the Breast with Smoothened (SMO) Mutation: Case Report and review of the Literature

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Transmutation of Sweat Glands - Eccrine Porocarcinoma

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Characterization of rpoB Gene Mutations Associated with Rifampicin Resistance in Multidrug Resistant Tuberculosis Patients Co-infected with HIV from Southern India.

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Genetic-Mathematical Modelling of Mutational Processes in a Population

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An Algorithm to Predict the Possible SARS-CoV-2 Mutations

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A New Gene Mutation of PRKAR1A was found in a Carney Complex Case

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Targeting Mutational Landscape of TP53 in patients diagnosed with Oral Cancer living in Senegal

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Psychosomatics: Exploring the Role of the Mind-Body Connection in Causing Physical Illnesses

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Prolonged survival of Diamond-Blackfan anemia and RPS19 mutation: an observation in Togo

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A Trio Study Showing Novel Gene Mutation In LAMB3 Causing Junctional Epidermolysis Bullosa (Intermediate/ Severe)

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Pain Perception Modulates Synaptic and Somatic Plasticity in the Dentate Gyrus of Rats

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Understanding Inherited Bleeding Disorders: Genetic Mutations in Blood Coagulation Factors and Regulatory Proteins

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Disruption of Hydrogen Bonding Network Decreases Catalytic Diversity of Chloroperoxidase via Abolishing Both Chlorination and Dismutation Activities

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Reflections on Vitale’s & Hew Len’s book “Zero Limits” (2007): Holistic Psychosomatic and Spiritual Implications

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