Sendai Virus
Sendai virus, also known as rodent parainfluenza virus, is a species of negative-sense single-stranded RNA virus belonging to the family Paramyxoviridae. It is an important model organism for studying the respiratory virus-host interactions and its importance in the pathogenesis of human respiratory diseases, such as bronchiolitis, pneumonia, and croup in children. It is also used in the development of vaccines and antiviral drugs. The Sendai virus is capable of infecting a variety of mammals and birds, leading to various clinical manifestations, depending on the species infected. In mice, the virus causes acute respiratory illness, while in pigs and horses, it can cause encephalitis. In humans, it causes a mild, self-limiting upper respiratory tract illness.
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