Nucleotide Excision Repair

Nucleotide Excision Repair (NER) is a DNA repair process that plays an essential role in protecting cells from damage caused by exposure to ultraviolet (UV) light and other environmental sources. NER removes damaged or altered nucleotides from DNA and replaces them with healthy ones, ensuring the cell’s genetic material remains intact. NER is critical for the maintenance of genetic integrity, and its dysfunction can lead to increased rates of mutation, cell death, and a wide range of diseases, including cancer. Therefore, understanding the mechanisms of NER can help us develop better treatments for genetic and cancer-related diseases.