Research Topic · Peer-Reviewed

Candida

Candida is a genus of yeasts that colonise the skin and mucosal surfaces of humans as part of the normal microbiota yet behave as opportunistic pathogens, producing infections known collectively as candidiasis. It includes Candida albicans, long the most frequently isolated clinical species, together with non-albica…

Curated from this journal's research 📚 9 peer-reviewed articles cited Cited 21× across the literature 🔖 ISSN 2997-1977 🗓 Reviewed August 2026

Overview

Candida is a genus of yeasts that colonise the skin and mucosal surfaces of humans as part of the normal microbiota yet behave as opportunistic pathogens, producing infections known collectively as candidiasis. It includes Candida albicans, long the most frequently isolated clinical species, together with non-albicans species such as C. glabrata, C. tropicalis, C. parapsilosis, and C. krusei, which vary in virulence and susceptibility to antifungal agents. Disease develops when host defences are weakened or the resident microbial balance is disrupted, permitting overgrowth and tissue invasion. Important virulence determinants include the reversible transition between yeast and filamentous hyphal forms, adherence to host tissues and the formation of biofilms on mucosa and medical devices, and the secretion of degradative enzymes. Clinical manifestations span superficial mucocutaneous infections, such as oral and vulvovaginal thrush, and life-threatening invasive or systemic candidiasis in immunocompromised, critically ill, or hospitalised patients. Diagnosis rests on culture, species identification, and antifungal susceptibility testing, while treatment employs azole, echinocandin, and polyene drugs, with management complicated by emerging resistance in certain species. Research relevant to this genus addresses the prevalence and antifungal susceptibility of clinical isolates, computational and peptide-based strategies to inhibit essential C. albicans proteins, and the behaviour of pathogenic and spoilage yeasts, supporting the diagnosis, prevention, and treatment of candidal disease.

Research published in this journal

9 peer-reviewed articles, ranked by relevance. Each links to its DOI.

How this research is being cited

The 9 articles above have been cited 21 times in the scholarly literature. Citation data via OpenAlex and Crossref, updated Jun 2026.

A sample of recent works citing this journal's research on Candida, linking to each citing work.

Editorial oversight

Curated from peer-reviewed research published in Diseases (ISSN 2997-1977).

Journal editorial board
Charles Edward Rupprecht · United States Dr. Md. Rabiul Islam · Bangladesh Madalena Barroso · Germany

This page summarises published research for orientation; it is not medical or professional advice.