Chief Cells
Chief cells are ATP-producing epithelial cells located in the gastric glands of the stomach. They secrete a potent proteolytic enzyme, pepsinogen into the gastric lumen, which, when activated, helps to break down proteins in food for digestion. Chief cells also secrete mucus to protect the stomach lining from digestive acids. Chief cells are an essential component of the gastric system and are responsible for the secretion of hydrochloric acid and very important to the digestion process. They have also been implicated in metabolic and physiological disorders such as gastric ulcers and cancer.
← Journal of Digestive Disorders And Diagnosis