Research Topic · Peer-Reviewed

Therapy Resistant Depression

Therapy resistant depression is a mental disorder in which symptoms of depression persist even when traditional forms of therapy such as medication and psychotherapy are used. This type of depression is characterized by serious symptoms such as difficulties with routine activities, insomnia, lack of concentration, a…

Curated from this journal's research 📚 1 peer-reviewed article cited Cited 1× across the literature 🔖 ISSN 2476-1710 🗓 Reviewed June 2026

Overview

Therapy resistant depression is a mental disorder in which symptoms of depression persist even when traditional forms of therapy such as medication and psychotherapy are used. This type of depression is characterized by serious symptoms such as difficulties with routine activities, insomnia, lack of concentration, and a feeling of hopelessness or helplessness. People with therapy resistant depression are often at an increased risk for suicide. Fortunately, early identification and treatment can improve quality of life and reduce the risk of suicide. Treatment options may include a combination of medications, cognitive behavioral therapy, psychotherapy, or even electroconvulsive therapy. With proper support and treatment, people with therapy resistant depression can live full and successful lives.

Research published in this journal

1 peer-reviewed article, ranked by relevance. Each links to its DOI.

How this research is being cited

The 1 article above has been cited 1 time in the scholarly literature. Citation data via OpenAlex and Crossref, updated Oct 2025.

A sample of recent works citing this journal's research on Therapy Resistant Depression, linking to each citing work.

Editorial oversight

Curated from peer-reviewed research published in Depression And Therapy (ISSN 2476-1710).

Journal editorial board
Ladislav Volicer · United States Roberto Maniglio · Italy

This page summarises published research for orientation; it is not medical or professional advice.