Depressive Disorder, Treatment-resistant

Depressive Disorder, also called Treatment-Resistant Depression, is a type of clinical depression that is difficult to treat. It is characterized by a persistent and disabling sadness, fatigue, difficulty in concentration, and a loss of interest in activities that used to bring pleasure. Treatment-resistant depression is a severe mental health disorder that affects millions of people worldwide. In severe cases, it can interfere with a person’s ability to manage their daily life. Traditional treatments such as antidepressant medications and psychotherapy may not be enough to treat it, so alternative therapies such as transcranial magnetic stimulation (TMS), electroconvulsive therapy (ECT), and brain stimulation therapies are sometimes used. With proper treatment, individuals living with treatment-resistant depression can be successfully managed and lead normal, productive lives.