Research Topic · Peer-Reviewed

Hiv-1

HIV-1 is the predominant type of the human immunodeficiency virus and the cause of the majority of HIV infections worldwide. A lentivirus of the retrovirus family, it carries a positive-sense RNA genome that, after entry via CD4 and a chemokine co-receptor, is reverse-transcribed by viral reverse transcriptase and i…

Curated from this journal's research 📚 12 peer-reviewed articles cited Cited 23× across the literature 🔖 ISSN 2691-8862 🗓 Reviewed October 2026

Overview

HIV-1 is the predominant type of the human immunodeficiency virus and the cause of the majority of HIV infections worldwide. A lentivirus of the retrovirus family, it carries a positive-sense RNA genome that, after entry via CD4 and a chemokine co-receptor, is reverse-transcribed by viral reverse transcriptase and integrated into host DNA; maturation of new virions depends on cleavage of viral polyproteins by HIV-1 protease. These enzymatic steps, reverse transcription, integration, and protease-mediated maturation, are the principal targets of antiretroviral drugs, and the virus's high replication and mutation rates drive antigenic diversity and the emergence of drug resistance. HIV-1 progressively depletes CD4-positive T cells, producing immunodeficiency, and is transmitted through blood, sexual contact, and from mother to child. The peer-reviewed research collected here in the journal's HIV and infectious-disease corpus reflects these themes, including antioxidant status, CD4 count and viral load in patients on combination antiretroviral therapy, T-cell vaccination hypotheses for eliciting HIV-1-specific responses, molecular docking of phytocompounds against HIV-1 reverse transcriptase and protease, clinical and immunological effects of botanical preparations in HIV-1-seropositive individuals, phytochemical approaches proposed to arrest HIV-1 progression, HIV self-testing and pre-exposure prophylaxis adherence, and false-positive rapid testing. Together they situate HIV-1 within its molecular biology, treatment targets, and prevention strategies.

Research published in this journal

12 peer-reviewed articles, ranked by relevance. Each links to its DOI.

How this research is being cited

The 12 articles above have been cited 23 times in the scholarly literature. Citation data via OpenAlex and Crossref, updated Jun 2026.

A sample of recent works citing this journal's research on Hiv-1, linking to each citing work.

Editorial oversight

Curated from peer-reviewed research published in Current Viruses and Treatment Methodologies (ISSN 2691-8862).

Journal editorial board
Dr. Mohammad Shayestehpour · Iran Dr. Andrea Martins da Silva · Brazil Dr. Anantha Harijith · United States

This page summarises published research for orientation; it is not medical or professional advice.