Nonalcoholic Steatohepatitis

Nonalcoholic steatohepatitis (NASH) is an increasingly common condition that occurs when fat builds up in the liver and causes damage to the liver cells. It is associated with obesity, diabetes, and hyperlipidemia, as well as a family history of metabolic disorders. It is estimated that up to 5% of adults in the United States have NASH, and the condition is expected to become a leading contributor to liver cirrhosis and the need for liver transplant in the next decade. The primary treatment for NASH is lifestyle modifications, such as weight loss and exercise, and medications, such as insulin sensitizers, fibrates, and statins. Early diagnosis and treatment of NASH can help prevent progression to cirrhosis or other serious complications.