Research Topic · Peer-Reviewed

Hirschsprung Disease

Hirschsprung disease (HD) is a rare condition, which affects the large intestine of newborn babies. It occurs when nerve cells in the gut do not form properly in the womb, leaving some portions of the intestine without the ability to coordinate muscle movement, known as the enteric nervous system. As a result, waste…

Curated from this journal's research 📚 1 peer-reviewed article cited 🔖 ISSN 2471-7061 🗓 Reviewed June 2026

Overview

Hirschsprung disease (HD) is a rare condition, which affects the large intestine of newborn babies. It occurs when nerve cells in the gut do not form properly in the womb, leaving some portions of the intestine without the ability to coordinate muscle movement, known as the enteric nervous system. As a result, waste is not able to move through the section of the intestine, resulting in an obstruction and the inability to have bowel movements. HD is treated with surgery to remove the portion of the intestine where the nerve cells are missing, followed by anastomosis of the healthy portions of the intestine. In some cases, a colostomy may be required. Early diagnosis and prompt treatment are essential for long-term health outcomes and quality of life for children affected by HD.

Research published in this journal

1 peer-reviewed article, ranked by relevance. Each links to its DOI.

Editorial oversight

Curated from peer-reviewed research published in Colon And Rectal Cancer (ISSN 2471-7061).

Journal editorial board
Frank A. Frizelle · New Zealand Gennaro Galizia · Italy Tamotsu Tsukahara · Japan

This page summarises published research for orientation; it is not medical or professional advice.