Anal Cancer

Overview

Anal cancer is a rare, malignant form of cancer which begins in the cells of the anus. It is most commonly caused by infection with the Human Papillomavirus (HPV), although other factors such as smoking and having a weakened immune system can increase the risk of developing it. Symptoms of anal cancer may include such as rectal bleeding, pain, and itching. While most cases of anal cancer can be treated with surgery, radiation, and/or chemotherapy, early detection is key. Anal cancer is an important health issue as it is often overlooked or misdiagnosed. Screening and early detection through anal Pap tests, as well as a healthy lifestyle with HPV vaccination, are critical in the prevention and early detection of anal cancer. Despite the rising incidence of HIV, which is a risk factor for anal cancer, new treatments, such as immunotherapies and combination treatments, have improved the chance of survival for those with anal cancer.

Research published in this journal

2 peer-reviewed articles, ranked by relevance. Each links to its DOI.

How this research is being cited

The 2 articles above have been cited 3 times in the scholarly literature. Citation data via OpenAlex and Crossref, updated Oct 2025.

• Anti-oncogenic effects of dutasteride, a dual 5-alpha reductase inhibitor and a drug for benign prostate hyperplasia, in bladder cancer
  Jaekwon Seok et al. · 2023 · Journal of Translational Medicine
• J591 functionalized paclitaxel loaded PLGA nanoparticles successfully inhibited PSMA overexpressing LNCaP cells
  Iman Ehsan et al. · 2022 · Journal of Drug Delivery Science and Technology
• Complementary and Alternative Treatments for Cancer Prevention and Cure (Part 1)
  2019 · Journal of Experimental and Clinical Toxicology

A sample of recent works citing this journal's research on Anal Cancer, linking to each citing work.

This page summarises published research for orientation; it is not medical or professional advice.

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