Journal of Clinical Research In HIV AIDS And Prevention

Journal of Clinical Research In HIV AIDS And Prevention

Journal of Clinical Research in HIV AIDS and Prevention

Current Issue Volume No: 2 Issue No: 2

Case Report Open Access Available online freely Peer Reviewed Citation

Painful Lesions in an HIV-1 Seropositive African Woman.

1National Institute for Infectious Diseases

Author Contributions
Received 28 Feb 2013; Accepted 24 Jul 2014; Published 21 May 2015;

Academic Editor: Katie Kramer, CEO/Principal The Bridging Group, LLC Oakland, CA.

Checked for plagiarism: Yes

Review by: Single-blind

Copyright ©  2015 Stefano Di Bella, et al.

Creative Commons License     This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

Competing interests

The authors have declared that no competing interests exist.


Stefano Di Bella, Fabrizio Taglietti, Nicola Petrosillo (2015) Painful Lesions in an HIV-1 Seropositive African Woman.. Journal of Clinical Research In HIV AIDS And Prevention - 2(2):28-28.

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DOI 10.14302/issn.2324-7339.jcrhap-13-235

Case Report

A 43 year-old woman seropositive for human immunodeficiency virus (HIV) complained of discomfort and burning pain in her perineal region. Clinical examination revealed multiple painful superficial ulcers. Serological tests for syphilis and swabs for Haemophilusducreyi were negative. CD4 cell count was 78 per cubic millimeter. A polymerase-chain-reaction assay performed on lesion swabs resulted positive for herpes simplex virus type 2 (HSV-2). Serology for herpes simplex virus type 1 and type 2 were both positive (IgG) suggesting recurrent HSV-2 infection. The patient underwent treatment with oral acyclovir 400 mg 5 times per day for 14 days with complete healing of the lesions and pain relief. HSV-2 infection both increases the risk of HIV acquisition and transmission, moreover genital herpes reactivates frequently in people infected with HIV 1. The persistence of herpes simplex ulcers for more than one month is an AIDS defining condition 2.

Figure 1.HIV-1 seropositive African woman
 HIV-1 seropositive African woman


  1. 1Gupta R, Warren T, Wald A. (2007) Genital herpes. , Lancet 370, 2127-37.
  1. 2Selik R M, Mokotoff E D, Branson B. (2014) Revised Surveillance Case Definition for HIV Infection – United States. , MMWR Recomm Rep 63, 1-10.