Complement Activation

Complement activation is an important process in the human immune system. The complement system, composed of a group of proteins, is involved in immune system defense against invading pathogens, such as viruses and bacteria. Complement activation occurs when one of these proteins binds to a pathogen and triggers a cascade of reactions. This ultimately leads to lysis and destruction of the pathogen. Complement activation also plays a role in inflammation by furthering the recruitment of defense cells, such as white blood cells, and facilitating the elimination of dead cells. Thus, complement activation is integral to the human immune response, and its dysfunction can result in a weakened immune system and contribute to increased susceptibility to infections.