Chromosome-associated Diseases
Chromosome-associated diseases are genetic diseases caused by changes in the structure or number of chromosomes, as compared to the normal number and structure of chromosomes in a healthy individual. These changes can be inherited or acquired in an individual’s lifetime and can result in physical, mental or behavioural disorders. Examples of such diseases include Down Syndrome, Klinefelter Syndrome, Patau Syndrome, and Turner Syndrome. Significant advances in genetics and molecular and cell biology have increased our understanding of how changes in chromosomes can cause human diseases. The diagnosis and treatment of chromosome-associated diseases are based on careful analysis of clinical, cytogenetic, molecular and epigenetic features, which can lead to the development of new and more effective therapies.
← Journal of Chromosomes