The authors have declared that no competing interests exist.
Currently, there is a paradoxical situation where the dominant opinion in medicine recognizes the harmfulness of dysfunction of such barrier structures as the cardia, pylorus, sphincter of Oddi, heart valves, valves of the veins of the lower extremities, etc., but ignores the failure of the ileocecal obturator (bauginium damper) or its absence as a possible cause of the pathology of the digestive system, as well as various extraintestinal diseases
But also I.I. Grekov (1952) expressed his position
Currently, there is a paradoxical situation where the dominant opinion in medicine recognizes the harmfulness of dysfunction of such barrier structures as the cardia, pylorus, sphincter of Oddi, heart valves, valves of the veins of the lower extremities, etc., but ignores the failure of the ileocecal obturator (bauginium damper) or its absence as a possible cause of the pathology of the digestive system, as well as various extraintestinal diseases
But also I.I. Grekov (1952) expressed his position
We assign one of the leading roles in the digestive system to the ileocecal obturator, which delimits the functions of the small and large intestines, isolates the small intestine from reflux of the l arge intestine contents, which differs sharply in chemical composition, physical state, and bacterial spectrum
Vital products of microorganisms (indole, phenol, cresol, skatol, catechol, carbolic acid, hydrogen sulfide, mercaptan, ethane, methane, etc.) are absorbed into the blood and cause auto-toxicity phenomena. These metabolites cannot be sufficiently detoxified, especially for liver diseases
SIBR leads to the development of putrefactive and fermentative processes in the small intestine. At the same time, the barrier role of the intestinal wall is violated
All authors recognize NLB as one of the anatomical causes of SIBR, but they have no therapeutic effect on it
M. Brotman
Some authors suggest that through the formation of carcinogens from bile acids, bacteroids may contribute to an increased incidence of colon cancer
When performing a right-sided hemicolectomy, the antireflux apparatus (bauginium flap) is removed and the ileocecal transition plays a major role in preventing colonic-small intestinal reflux and the development of a number of pathological conditions, including bacterial overgrowth syndrome (SIBR) in the small intestine
One of the leading links in the pathogenesis of SIBR is the premature deconjugation of primary bile acids (FA)
One of the causes of SIBR is the retrograde colonization of the small intestine from the lower sections of the gastrointestinal tract as a result of removal of the bauginium flap during right-sided hemicolectomy, both on a planned and emergency basis
The elimination of NSC and the use of antireflux small-intestinal anastomosis open up the possibility of surgical prevention of precancerous diseases and colon cancer