NADPH Oxidase–Mediated ROS
Generation NADPH oxidase is an enzyme complex responsible for generating reactive oxygen species (ROS) in the cells of many organisms, including humans. ROS play a significant role in cell signalling and homeostasis, and dysregulation of their production is linked to a variety of diseases, including cancer, diabetes, and neurodegeneration. NADPH oxidase-mediated ROS generation is involved in physiological processes such as vasodilation, apoptosis, and immune cell activation, and has been implicated in the development of a number of pathologies, including hypertension, atherosclerosis, and inflammatory diseases. NADPH oxidase-mediated ROS production is therefore an important area of research in the fields of medicine, pharmacology, and biochemistry.
← Journal of Antioxidant Activity