Research Topic · Peer-Reviewed

Dementia with Lewy Bodies

Dementia with Lewy bodies (DLB) is a progressive neurodegenerative disorder and one of the most common forms of dementia after Alzheimer's disease. It is characterized by a decline in cognition accompanied by distinctive features such as fluctuating attention and alertness, recurrent and detailed visual hallucinatio…

Curated from this journal's research 📚 1 peer-reviewed article cited Cited 9× across the literature 🔖 ISSN 2998-4211 🗓 Reviewed June 2026

Overview

Dementia with Lewy bodies (DLB) is a progressive neurodegenerative disorder and one of the most common forms of dementia after Alzheimer's disease. It is characterized by a decline in cognition accompanied by distinctive features such as fluctuating attention and alertness, recurrent and detailed visual hallucinations, parkinsonian motor signs including rigidity and slowness of movement, and disturbances of sleep. The disorder is associated with the abnormal accumulation of the protein alpha-synuclein into intracellular deposits known as Lewy bodies within neurons, which disrupts brain function. Diagnosis can be challenging because its features overlap with those of Alzheimer's disease and Parkinson's disease dementia, and management focuses on addressing cognitive, motor, and neuropsychiatric symptoms while avoiding medications that can worsen the condition. Research relevant to dementia in the OpenAccessPub portfolio includes work examining the neurobiological distinctions between aggression and agitation in persons with dementia, which addresses the behavioral and neuropsychiatric disturbances that complicate care in dementia syndromes. Such studies inform understanding of the symptom burden shared across dementia types. This page presents an encyclopedic overview of dementia with Lewy bodies, its clinical features, and its underlying neuropathology, alongside related dementia research.

Research published in this journal

1 peer-reviewed article, ranked by relevance. Each links to its DOI.

How this research is being cited

The 1 article above has been cited 9 times in the scholarly literature. Citation data via OpenAlex and Crossref, updated Jun 2026.

A sample of recent works citing this journal's research on Dementia with Lewy Bodies, linking to each citing work.

Editorial oversight

Curated from peer-reviewed research published in Alzheimer's Research and Therapy (ISSN 2998-4211).

Journal editorial board
Aysun Cetinyurek Yavuz · Netherlands Elvis Freeman Acquah · Australia Silvia Ingala · Netherlands

This page summarises published research for orientation; it is not medical or professional advice.