Research Topic · Peer-Reviewed

Alzheimer Disease

Alzheimer disease is a progressive, irreversible neurodegenerative disorder and the most common form of dementia, characterised by deterioration of memory, reasoning, language, and behaviour, predominantly affecting older adults. Its pathology centres on amyloid-beta plaques, neurofibrillary tangles of hyperphosphor…

Curated from this journal's research 📚 12 peer-reviewed articles cited Cited 30× across the literature 🔖 ISSN 2998-4211 🗓 Reviewed July 2026

Overview

Alzheimer disease is a progressive, irreversible neurodegenerative disorder and the most common form of dementia, characterised by deterioration of memory, reasoning, language, and behaviour, predominantly affecting older adults. Its pathology centres on amyloid-beta plaques, neurofibrillary tangles of hyperphosphorylated tau, synaptic and neuronal loss, and medial temporal and cortical atrophy, with risk influenced by genetic, vascular, metabolic, and lifestyle factors. Although no curative treatment exists, early diagnosis and intervention can support quality of life, driving research into biomarkers, imaging, therapeutic targets, and non-pharmacological care. The research collected here reflects this scope through studies of assistive technology and cognitive-behavioural programmes for adaptive skills, non-pharmacological interventions for disrupted sleep in moderate-to-severe dementia, early prediction using optical coherence tomography imaging, caregiver knowledge gaps and misconceptions, vagus nerve stimulation as a potential treatment, circular RNAs in Alzheimer's disease, and the relationship between cortisol, depression, and medial temporal lobe atrophy in mild cognitive impairment. Further work addresses aggression and agitation in dementia and bioinformatics in disease diagnosis. Together they span detection, molecular mechanisms, therapy, behavioural management, and caregiving. The journal publishes peer-reviewed research on the mechanisms, diagnosis, treatment, and care of Alzheimer disease and related dementias.

Research published in this journal

12 peer-reviewed articles, ranked by relevance. Each links to its DOI.

2017

JALR. New Journal, Old questions, Fresh insights

Paganelli RobertoCorresponding author
Department of Medicine & Sciences of Aging, University “G. d’Annunzio” of Chieti-Pescara, Italy
Alzheimer's Research and Therapy doi:10.14302/issn.2998-4211.jalr-17-1884
2015

Epigenetics and Nutrition

Lundstrom KennethCorresponding author
PanTherapeuitcs, Rue des Remparts 4, CH1095 Lutry, Switzerland
International Journal of Nutrition Cited by 2 doi:10.14302/issn.2379-7835.ijn-14-603

How this research is being cited

The 12 articles above have been cited 30 times in the scholarly literature. Citation data via OpenAlex and Crossref, updated Jun 2026.

A sample of recent works citing this journal's research on Alzheimer Disease, linking to each citing work.

Editorial oversight

Curated from peer-reviewed research published in Alzheimer's Research and Therapy (ISSN 2998-4211).

Journal editorial board
Aysun Cetinyurek Yavuz · Netherlands Elvis Freeman Acquah · Australia Silvia Ingala · Denmark

This page summarises published research for orientation; it is not medical or professional advice.