Research Topic · Peer-Reviewed

Animal Models of Aging

Animal models of aging are laboratory organisms used to study the biological mechanisms, pathological changes, and potential interventions associated with the aging process in controlled experimental settings. Research published in Aging Research and Healthcare has employed animal models, particularly rodent systems…

Curated from this journal's research 📚 12 peer-reviewed articles cited Cited 11× across the literature 🔖 ISSN 2474-7785 🗓 Reviewed June 2026

Overview

Animal models of aging are laboratory organisms used to study the biological mechanisms, pathological changes, and potential interventions associated with the aging process in controlled experimental settings. Research published in Aging Research and Healthcare has employed animal models, particularly rodent systems, to investigate specific aspects of age-related dysfunction and therapeutic approaches. Studies have utilized D-galactose-induced aging models in Sprague Dawley rats to evaluate immunomodulatory effects of novel formulations and to examine interventions aimed at preventing aging markers and improving longevity. These experimental models allow researchers to assess biomarkers of aging, test potential anti-aging compounds, and explore mechanisms underlying age-related conditions under standardized laboratory conditions. The journal has also published work examining muscle dysfunction in aging contexts and exploring therapeutic possibilities such as melatonin supplementation. Animal models remain essential tools in aging research because they enable systematic investigation of aging processes across shorter timescales than human studies allow, facilitate controlled experimental manipulation, and provide opportunities to test interventions before clinical translation. Understanding how aging manifests in model organisms contributes to broader knowledge about age-related physiological decline and informs the development of strategies to promote healthy aging in human populations.

Research published in this journal

12 peer-reviewed articles, ranked by relevance. Each links to its DOI.

How this research is being cited

The 12 articles above have been cited 11 times in the scholarly literature. Citation data via OpenAlex and Crossref, updated Jun 2026.

A sample of recent works citing this journal's research on Animal Models of Aging, linking to each citing work.

Editorial oversight

Curated from peer-reviewed research published in Aging Research And Healthcare (ISSN 2474-7785).

Journal editorial board
Anna Aiello · Italy Juan Manuel Carmona Torres · Spain IAN JAMES MARTINS · Australia

This page summarises published research for orientation; it is not medical or professional advice.