Research Topic · Peer-Reviewed

Leukocyte Adhesion

Deficiency (LAD) Leukocyte Adhesion Deficiency (LAD) is a rare disease that is caused by genetic defects in the body’s ability to make adhesion molecules, which are needed for white blood cells (leukocytes) to move around the body and fight infections. People with LAD have an increased susceptibility to bacterial i…

Curated from this journal's research 📚 4 peer-reviewed articles cited Cited 11× across the literature 🗓 Reviewed June 2026

Overview

Deficiency (LAD) Leukocyte Adhesion Deficiency (LAD) is a rare disease that is caused by genetic defects in the body’s ability to make adhesion molecules, which are needed for white blood cells (leukocytes) to move around the body and fight infections. People with LAD have an increased susceptibility to bacterial infections, which can become life-threatening if not treated quickly. In addition, many of these infections are caused by very virulent bacteria, including Staphylococcus aureus and Mycobacterium avium, which are difficult to treat. Treatment for LAD is focused on managing the infection and preventing it from occurring. This can include antibiotics, supportive care, bone marrow transplantation and gene therapy. With early diagnosis and prompt treatment, people with LAD can lead normal and healthy lives.

Research published in this journal

4 peer-reviewed articles, ranked by relevance. Each links to its DOI.

How this research is being cited

The 4 articles above have been cited 11 times in the scholarly literature. Citation data via OpenAlex and Crossref, updated Jun 2026.

A sample of recent works citing this journal's research on Leukocyte Adhesion, linking to each citing work.

Editorial oversight

Curated from peer-reviewed research published in Advances in Leukemia.

Journal editorial board
Hang Su · United States Ewelina Grywalska · Poland Antonio Ruggiero · Italy

This page summarises published research for orientation; it is not medical or professional advice.