RNA Based Therapeutics

RNA-based therapeutics are a new and exciting field in biotechnology and medicine, offering an innovative approach to treating a wide variety of diseases. RNA molecules act as messengers, transmitting genetic information from one cell to the next and regulating the expression of proteins. RNA-based therapeutics are designed to target specific RNA molecules to either up- or down-regulate protein expression. This can result in the modification of disease-causing proteins or the activation of genes that promote health. These therapies are showing great promise in treating diseases such as cancer, cardiovascular disease, neurological disorders, and infectious diseases. They can be used as single treatments or in combination with other types of therapies, such as gene editing or gene therapy. By targeting specific molecules, they offer an effective and safe approach to treating a wide range of diseases.

← Journal of Advanced Therapeutic Science

Related Articles

136 article(s) found

Editorial for Journal of Proteomics and Genomics Research

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Editorial for Journal of Proteomics and Genomics Research: Second Issue

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Testing Maternal-Fetal Genotype Incompatibility with Mother-Offspring Pair Data

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The Use of Mirnas as Activators of Dental Implant Surfaces, A Review

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Determination of the Proteomic Response to Lapatinib Treatment using a Comprehensive and Reproducible Ion-Current-Based Proteomics Strategy

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Discovery and Quantification in Mass Spectrometry-Based Proteomics

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Development of a Model-Based Noninvasive Glucose Monitoring Device for Non-Insulin Dependent People

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Evaluating the Efficacy of Gene Silencing in Dopaminergic Neuronal Cells In-Vitro using Gold Nanorods (GNR) with Different Surface Properties Complexed to DARPP-32 siRNA.

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Development of Poly-ε-Caprolactone Based Nanoadjuvant for Effective Vaccination Against Tuberculosis

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Editorial of the First Issue - Journal of New Developments in Chemistry

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Vegetarianism in Food-Based Dietary Guidelines

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MicroRNA Profiling of Differentiated, Poorly Differentiated and Anaplastic Thyroid Carcinoma, a Comparative Approach

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Below What Hemoglobin Concentration in Pregnancy is there an Increased Risk of Maternal or Fetal Adverse Effects?

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Pregnancy with Maternal Caroli’s Disease - Case Report

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MicroRNAs: As A Novel Potential Tool for Diagnosis, Prognosis, and Therapeutic Agents in Hypertension.

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MicroRNA-1285 Might Potentially Regulate OCT4 Gene Expression by Direct Targeting of its Promoter

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Cholesterol-Conjugated siRNA Accumulates in the Different Hematopoietic and Lymphoid Cells.

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Arm Span is an Alternative to Standing Height for Calculation of Body Mass Index (BMI) amongst Older Adults

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The Therapeutic Effect of Bilateral Alternating Stimulation Tactile Form Technology on the Stress Response

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Mental Health Promotion for the ‘In-Betweeners’: The Rationale and Effectiveness of Community-Based Mentoring and Coaching Schemes for Primary School-Aged Children.

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Using The RE-AIM Framework to Evaluate A Community-Based Smoke Alarm Installation Program

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Preliminary Survey on The Termite Mounds, Their Interior Geometrics and The Termite Prevention from Infrastructural Construction at New Site of Ndola International Airport in Zambia

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Addressing the gastrointestinal health associated with schizophrenia: The argument for a new nutrition-based intervention

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“On the Road to A Better Life”: An Innovative Suicide Prevention Program Based on The Realization of Meaningful Personal Goals

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Internal Jugular Vein and Transverse Sinus Thrombosis as a Complication of a Chronic Ethmoidal Sinusitis

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Non-Hodgkin Lymphoma of External Auditory Canal – Uncommon Location and Related Risk Factors

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MicroRNA: New Era for Therapeutic Strategy in Ischaemic Heart Disease

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Compliance to Company Based Colorectal Cancer Screening in Germany using Fecal Immunochemical Test (FIT) - Results of Almost Half a Million FIT Tests

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Ketamine-Based Treatment of MDD: A Biologist’s Perspective

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A Cost Analysis of Systematic Vitamin D Supplementation in the Elderly Versus Supplementation Based on Assessed Requirements

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Journal of Enzymes for a New Applicable Knowledge

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This Isn’t Just a Phantom, Menopause, But You Can Vent Your Feelings - Qualitative Evaluation of Evidence Based Health Information (EBHI) Material

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JALR. New Journal, Old questions, Fresh insights

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Mild Ovarian Stimulation has Similar Live Birth Rates as Compared with Hyper Stimulation for Treatment of Poor Responding IVF Patients of Advanced Maternal Age

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Evaluation of an External Quality Assessment Program for HIV Testing in Tigray North Ethiopia 2016

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International Journal of Chemotherapy and Practice; A Novel Journal for Therapeutic Researches

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Intrauterine Deaths in North-Eastern Hungary with National and International Comparison

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Future of Journal of Medical and Psychological Trauma: Tips for the Authors and Editors

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Morphological Features of Wild Mallard Ducks on Postnatal Growth Based on Functional Analysis of Capture-Recapture Data

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Ovarian Cancer Identification Based on Feature Weighting for High-Throughput Mass Spectrometry Data

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Diurnal Variation in the Core Interthreshold Zone in Women and its Sex Difference

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Journal of Diseases

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Bisphenol A Down-Regulates The mRNA Expression of Steroidogenic Genes and Induces Histopathological Changes in Testes Of Rats

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Using A “Superrooting”Cultivar of Taxus Chinensis Var. Mairei to Unravel Antioxidative Enzymes’ and Micrornas’ Role on Adventitious Rooting

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Journal of Sports and Exercise Medicine

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Evaluation of Some Sugar Beet Genotypes Under Drought Stress Based on Selection Indices

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Assessment of Biofield Energy Healing Based Vitamin D3 Effects on Bone Health Parameters Using Human Osteoblast Cell Line (MG-63)

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Method to Generate Electric Power and Hydrogen in the Absence Of External Energy

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Perioperative Period is a Critical Gap for Minimal Residual Cancer Cells Progression and Therapy: Biological and Molecular Based Evidences

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Genetic Diversity, Phylogenetic Tree and Principal Component Analysis Based on Morpho-Metric Traits of Assam Chilli

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Emerging Roles of Plant Circular RNAs

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Efficacy and Safety of Lycoprozen®, a Novel Tomato-Based Food Supplement in Patients with Benign Prostatic Hyperplasia

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Investigation of Antimicrobial Activity of the Extracts of the Leaves, Stembark and Root of Allanblackia floribunda: An Alternative Paradigm Shift Outcome.

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Quantification of Micrornas by Absolute Dpcr for the Diagnostic Screening of Colon Cancer

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Secular Trend in the Incidence of Japanese Employees with Thyroid Cancer Undergoing Thyroidectomy from 2005 to 2014: a Retrospective Descriptive Study Using an Employment-Based Insurance Claims Database

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First Geographical Record of Corymorpha bigelowi (Cnidaria: Hydrozoa, Corymorphidae) in the Northern Red Sea Coast of Egypt, Based on Morphological Description

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Women’s Empowerment and the Integration of Traditional Maternal and Child Healthcare with National Health Systems in the Republic of Guinea.

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Effect of Neosaxitoxin on Epidural Anesthesia in Cats: a Promising Alternative to Conventional Anesthetics

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Long Non-Coding RNAs Emerging as Potential Epigenetic Biomarkers for Tobacco and/or Alcohol-Induced Head and Neck Cancer

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Complementary and Alternative Treatments for Cancer Prevention and Cure (Part 1)

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A Feasibility Study of A Home-Based Program to Promote Perceived Adequate Milk

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Diaphragmatic Pacing as an Alternative to Mechanical Ventilation: Early Experience from a Developing Country

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International Comparison of Children’s Knowledge, Barriers and Reported Fluid Intake Across the School Day.

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Marangoni Effect in Second Grade Forced Convective Flow of Water Based Nanofluid

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Maternal Behavior Affects Child’s Attachment-Related Cortisol Stress Response

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Empowering Persons with Intellectual Disabilities Through Work/School Alternation: a Positive Case study

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Examination of Maternal Assets and Breast Milk Expression

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A Triple-Blind, Placebo-Controlled Randomized Trial of the Effect of Bilateral Alternating Somatosensory Stimulation on Reducing Stress-Related Cortisol and Anxiety During and After the Trier Social Stress Test

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Maternal Indigenous and Artisanal Coastal Nutrition, the SDG Imperative: A Suggested Renaissance of Ethics for Research and Tertiary Education in the Anthropocene Era

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Cell-Based Vital Organs Specific Biomarkers Assessment using Biofield Energy Based Novel Test Formulation

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Impact of Biofield Energy Treatment Based Test Formulation on Vital Organ Health Specific Biomarkers Using Cell Line Study

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In Vitro Cell-Based Biomarkers Study of Vital Organs: Impact of the Biofield Energy Based Test Formulation

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Mathematical Analysis of Alternative Power Systems in a Northern Wisconsin Home

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Allele Based Inference on Evolution and Extinction; A Genetic Drift Approach

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Use of a Partially Hydrolyzed 100% Whey-Based Infant Formula with Lactobacillus Reuteri in Infants with Caregiver-Perceived Intolerance

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How do College Students in India Respond to Gender-Based Violence (GBV)?

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Analysis and Forecast Based on the Kinetic Equation for Changing the Numerical Composition of Living Systems

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Growth Performance of Heteroclarias Juveniles Fed Graded Levels of Autoclaved Castor Seed (Ricinus communis L.) Cake Based Diets

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Closed Frequent Itemsets Mining Based on It-Tree

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Use of Microfluidic Assays to Develop Reliable and Economic Nucleic Acid Application Technologies, Employing MicroRNAs for the Diagnostic Screening of Colon Cancer in Human Stool in Low-Resource Settings

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Rate, Maternal and Fetal Outcome of Cesarean Delivery Performed by IESO at Shenen Gibe General Hospital, Jimma South West Ethiopia: A Descriptive Retrospective Data

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Assessment of Prescribing and Dispensing Practices Based on WHO Core Prescribing Indicators in Hospital and Community Pharmacies in Khartoum State - Sudan

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Use of Fluoride and Silver Ion Compounds in Three International School Based Oral Health Programs – A Case Report

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Community Based Study of Rural, Tribal Women Seeking Induced Abortions in a Extremely Low Resource Region

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Use of Microfluidic Assays to Develop Reliable and Economic Nucleic Acid Application Technologies, Employing MicroRNAs for the Diagnostic Screening of Colon Cancer in Human Stool in Low-Resource Settings

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Covid-19 Virus Sterilization Oven Based on Combination Between Ultraviolet and Infrared Emissions

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Preparation of Microwave Multi-Adsorbent Nanocomposites Based on Copper, Iron Carbonyl, Carbon Nanofiber, Graphite Nanoflake and Polypyrrole

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Coprological Examination of Ovine Fasciolosis in Horro District Community Based Sheep Breeding Program, Horro Guduru Wollega Zone, Western Ethiopia

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A Summary of Circular RNAs in Alzheimer's Disease

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Cell Therapy as an Alternative approach for COVID-19 Infection Consequences: A Non-Systematic Review

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Evaluation of Anti-oxidation and Therapeutic Effect of Biofield Energy Healing Based Novel Test Formulation Using TNBS (Tri Nitro Benzene Sulfonic Acid) - Induced Ulcerative Colitis in Sprague Dawley Rats

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Molecular Evolutionary Characteristics of the 2019 Novel Coronavirus (SARS-CoV-2) Contracted by Tunisian Citizens : Comparison and Relationship to Other Human and Animal Coronaviruses Based on Spike Glycoprotein-Coding Gene Sequences Analysis

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Evaluation of Vitamin D3 metabolite (25-OH Vit D3), Neurotransmitter (ACh), and the Expression of Proinflammatory Cytokines (IL-6 and TNF-α) in Tissue Homogenate after Administration of Biofield Energy Healing-based Novel Proprietary Test Formulation and Biofield Treatment per se to the Animals in Vitamin D3 Deficiency Diet (VDD)-induced Sprague Dawley Rats

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A Model-Based Estimation of Annual Long-Term Care Costs in Germany Following Post-Operative Cognitive Dysfunction (POCD) in Elderly Patients

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Palliative Care for Cancer Patients and their Relatives in Dutch Community-Based Psychosocial Support Centers (CBPSCs)

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Complementary Food Hygiene Practice among Mothers or Caregivers in Bale Zone, Southeast Ethiopia: A Community Based Cross-Sectional Study

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Elasticity Profile of Skin, Neuronal, Cardiac, and Skeletal Muscle Cells after Treatment with the Biofield Energy Healing-Based Proprietary Test Formulation

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Evaluation of Inflammatory Serum Cytokines after Treatment with the Consciousness Energy Healing Based Proprietary Test Formulation on Combination of Cecal Slurry, LPS and E. Coli Induced Systemic Inflammatory Response Syndrome (SIRS) in Sprague Dawley Rats

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Liver Disease: A Retrospective Hospital Based Study in Addis Ababa-Ethiopia

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Characterizing the Dynamics of Covid-19 Based on Data

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FDA Should Re-evaluate All mRNA Vaccines and Revoke Their Use Authorizations (The Short Version).

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Expression of Concern: Potential Risks and Unknown Effects of mRNA Vaccines on Population Health (6th Rev). Damages Are Being Materialized

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Clinical Use of Peptide-Based Formula (Peptamen Junior®, Nestle) in the Paediatric Population

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Design of Stopwatch based on STC89C52 Single Chip Microcomputer

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Review on Public Health Effects of Aflatoxins in Milk and Milk-Based Foodstuffs of Dairy Cow

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BaMtox, a Myotoxic Enzyme Isolated from the Venom of the Bothrops Alternatus

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Scrutinizing Famine Disaster Based On Rainfall Trend Investigation (A Case Study of Khorasan Razavi Province)

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Quality of Maternal & Newborns Health indicators in Western Province of Rwanda

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Perceived Barriers and Facilitators to Implementation of Maternal and Child Health Care by Community Health Workers in Rwanda: A Qualitative Study

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Epidemiological Profile of Intestinal Protozoan Infection in Dakar, Senegal: Results from Hospital-Based Survey

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Visualization of Myocardial Damage Based on Surface Heart Model

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Context Specific Complementary Feeding Recommendations for Children in Pakistan Based on Secondary Analysis of National Complementary Feeding Assessment and Pakistan Demographic Health Survey 2018

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Magnitude and Trends of Chronic Liver Disease: A Retrospective Hospital Based Study in Eastern Amhara Region, Northeast Ethiopia

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Soluble Biobased Substances in soil or Salicylic Acid on leaves affect the foliar pH and soil biovariability of Grapes-as explained by the NIR Spectroscopy of Litterbags and Teabags

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Distribution and Conservation Challenges of Diurnal Large Mammals in Bayo Community Managed Forest, Salamago Woreda, South Omo Zone, Southern Ethiopia

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GIS Based Approach for Analysis of Habitat Suitability and wildlife conservation for African Buffaloes (Syncerus caffer) at Dhati Welel National Park, Ethiopia

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Correlation Between Biochemical Oxygen Demand And Chemical Oxygen Demand, At High Salinity Bioreactor-Based, Wastewater Treatment Plant In Al-Hasa Saudi Arabia.

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Interventional Programs for Genetically Disabled People Through Evidence-Based Advocacy

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A Roadmap to Developing a Population-Based Colorectal Cancer Screening Program in Oman

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The Energy–Matter–Behavioral Model of Mental Health Hygiene: A Systems-Based Framework for Sustainable Well-Being

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EPIC® and High Reliability in Healthcare: An Evidence Based Commentary

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Determinants of Exclusive Breastfeeding Among Mothers of Infants Less Than Six Months of Age in Mogadishu: A Facility-Based Cross-Sectional Study

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Evaluating the Effectiveness of Quality Improvement Strategies in Mid-Level Private Healthcare Facilities of Lagos State: A Donabedian Model-Based Approach

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Stratified Analysis of Factors Associated With Mortality in Patients With COVID-19 Based on Cancer and Diabetes

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Dynamic MicroRNA-Expression in Plasma of Melanoma Patients Correlates With Progression, PD-L1 Status and Overall Survival

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A Network Pharmacology-Based Strategy For Predicting Therapy Targets Of Beta-Sitosterol In Treating Diabetic Retinopathy

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Toward A Diet Based on MicroRNA

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Newborns' MicroRNA Expression as Potential Biomarkers for Disease Diagnosis

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Internal Jugular Phlebectasia; A Challenging Neck Mass in Children

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Ecosystem-Based Fishery Management of Antarctic Krill (Euphausia superba) to Support Baleen Whales and other Predators Production Adapted for Potential Climate Change Effects

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Applying Cultural Humility During an International Collaboration Seeking to Optimize A Peaceful Coexistence Intervention in The Kingdom of Bahrain: Lessons Learned

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Prevalence of Burnout, Secondary Traumatic Stress, Anxiety, and Depression Among Maternal and Neonatal Healthcare Staff in Two Tertiary Hospitals in Zambia

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Factors Influencing Dietary Diversity and Nutritional Status Among Adolescent Pregnant Women in South-Eastern Tanzania: A Hospital-Based Cross-Sectional Study

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Uptake of Cervical Cancer Screening and Its Determinants among Refugee Women in Uganda: Insights from the Uganda Refugee Population-based HIV Impact Assessment

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Insect-Based Foods: A Comprehensive Review on Nutritional Benefits and Environmental Sustainability

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Soil Fertility Dynamics and Xanthomonas Wilt Incidence in Enset (Ensete Ventricosem) Based Farming at Chencha, Southern Ethiopia

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