International Journal of Human Anatomy
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    Embryogenesis and Applications of Fingerprints- a review

    Adamu LH 1       Taura MG 1 2    

    1Department of Anatomy, Faculty of Basic Medical Sciences, College of Health Sciences, Bayero University, Kano, Nigeria

    2Department of Anatomy, College of Medicine University of Bisha Kingdom of Saudi Arabia.

    Abstract

    Fingerprint is an impression made by the friction ridges that are almost parallel at constant crest to crest wavelength. The pattern is dominated by central features, such as whorls, loops, arches and triradii. Fingerprints have been used for several decades in forensic and medical sciences. The fingerprints characteristics such uniqueness, consistency and universality are the main features that are used by forensic experts in identification processes, are well developed during intra-uterine life. Understanding embryogenesis of fingerprints is essential in linking its features to some disease conditions. The purpose of this review was to highlight information regarding establishment, formation, hypotheses and factors affecting fingerprints. Applications of the fingerprints in forensic and medical sciences were also highlighted. Both environmental (in utero) and genetic factors have role to play in the formation of the fingerprints. The primary role of fingerprints is personal identification; these can be achieved through revealing sex, ethnicity, diet and lifestyle of an individual. In another perspective the fingerprints can be used as tools in diagnosis and ascertaining presence of disease conditions, however, this is population specific.

    Received 13 Apr 2017; Accepted 20 Jun 2017; Published 27 Jun 2017;

    Academic Editor:Shuji Kitahara, Massachusetts General Hospital/Harvard Medical School

    Checked for plagiarism: Yes

    Review by: Single-blind

    Copyright© 2017 Adamu LH, et al.

    License
    Creative Commons License    This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

    Competing interests

    The authors have declared that no competing interests exist.

    Citation:

    Adamu L, Taura M () Embryogenesis and Applications of Fingerprints- a review. International Journal of Human Anatomy - 1(1):1-8.
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    Introduction

    Fingerprint is an impression made by the friction ridges that are almost parallel at constant crest to crest wavelength. The pattern is dominated by central features, such as whorls, loops, arches and triradii. 1 Clear inspection reveals dozens of other imperfections such as ridge endings, ridge bifurcations, island ridges etc. The type and relative geometry of these dislocations form the bases of the uniqueness of the fingerprints. [1, 2]The uniqueness and consistency of the fingerprints throughout life, are some of the features used for personal identification. [2, 3] The role of genetic factor in embryogenesis of fingerprints necessitates its correlation with disease conditions. 4

    The purpose of this review was to highlight information regarding embryogenesisand application of the fingerprints patterns in forensic and medical sciences. This review may help in revealing information that is useful to forensic community in terms of establishment of identity. It may also provide additional information on the potential of fingerprint features as diagnostic and screening tools in some diseases condition.

    Materials and Methods

    Pubmed, Science direct data bases were used while some information were collected by direct searching using Google search engine. Reference lists of identified articles were explored for additional articles. Certain keywords were used alone or in combination which form the headings and subheading of the articles. In maintaining the focus of the review original research and reviewed articles were included. Case report and abstracts, editorial were excluded.

    EMBRYOLOGY OF FINGERPRINTS

    The epidermal ridge pattern depends upon the cornified layer of epidermis and dermal pattern. Proliferation of cells in the lower zone of epidermis resulted in projections in the dermis as regular spaced thickenings. The dermisalso projects upwards into the epidermal hollows, referred to as dermal papillae. This led to appearance of elevations on the surface of the skin known as epidermal ridges. [4, 5]

    Establishment of fingerprints

    The crucial events for the establishment of the epidermal ridge pattern take place from the 10th to 16th weeks of development. At 10th week, embryonal volar skin consists of the layered epidermis on top of more amorphous fibrous dermis. At that moment the epidermis consists of three layers; periderm on the outside, the intermediate layer and the basal layer at the interface of the dermis. [4, 6-12 ]

    During 11th week the basal layer of the epidermis consists of columnar cells whose axis is perpendicular to the skin surface. It’s observed that the basal layer becomes undulated, which quickly becomes prominent and form folds of the epidermis into dermis. These folds are called primary ridges which establish the future surface patterns which become well pronounced at the 16th week. Because fingerprints patterns are encoded at the interface between dermis, the pattern cannot be destroyed by superficial skin injuries. [4, 10, 13]

    Spread of epidermal ridges

    Primary ridge formation does not occur simultaneously on volar skin surface. The formation usually starts at a certain area in the middle of volar pad (which is called the ridge anlage) and along nail furrow, a little later along the interphalangeal flexion creases. The area of the ridge anlage usually coincides with the center of the whorl and loops if such pattern shows up. In this way, there are three ridge system on the fingertips (starting from the ridge anlage, the nail furrow and the flexion creases), which slowly spread over the fingertip. At the location where these ridge systems finally meet, triradii arises. [6, 7, 12, 13] This gives rises to complete fingerprints pattern (Figure 1). which is classified basically into loops, whorls and arches (Figure 2).

    Figure 1.
    Figure 1.
    Stages in spread of epidermal ridges and formation of triradii

    Figure 2.
    Figure 2.
    Three basic fingerprint patterns

    It’s likely from empirical evidence that the primary ridge system changes until the 16th week, when it becomes permanent. For example, it was observed that the number of minutiae significantly rises in that time. A possible reason for this observation could be a large growth rate of the finger compared with bridge of the ridges, which will lead to the insertion of new ridges as minutiae. 14

    Hypotheses of ridge formation

    The different hypotheses were established which are key to the understanding of the embryology of the fingerprints. Although there is no general consensus on the mechanism for ridge formation to date, the following hypotheses in Table 1prove to be very important in the understanding of fingerprints formation.

    Table 1.
    752475174307500Hypotheses Mechanism Limitation
    Folding and mechanical processes [6, 15, 16, 17, 18] Folding process, which is induced by differential growth and the process, is parallel to the largest growth stress. The sources of stress that produces the observed patterns not identify.
      Intense cell proliferation in the basal layer of the epidermis resulting in cylindrical cells, which evade the stress by folding toward the dermis.  
    Nerve [19, 20, 21] Fingertips are innervated by hexagonal pattern of axons whose wavelength roughly equals to the one of fingerprints. A ridge direction and ridge formation has still been observed in experiments where innervations was prevented.
    Fibroblast 22 Fibroblast cell pattern are similar to fingerprints pattern, thus it formation is induced by pre pattern of the fibroblast in the dermis. What induced the formation of the pre pattern of the fibroblast in the dermis not clear
    Biochemical 23 The repetition of the pattern was due to a specialized biochemical system (morphogens) allowing formation of the wrinkles in the fingerprints. The exact influence of each biochemical and mechanical factors on the formation of surface pattern becomes an experimental challenge.
    Mechanism and limitation of the hypotheses of ridge formation

    Factors influencing fingerprints features

    Several features are associated with fingerprints. The formation of fingerprints feature is influenced by several factors in utero. These factors can be summarized as follows Table 2: Factors influencing fingerprints features

    Table 2.
    762000592455000Factors Definition Features Comments
    Volar pads24 Temporary eminences of the skin surface that form during the 7th week of development Pattern ·   Highly rounds symmetrical pads whorls;
          ·   Less well developed asymmetric pad shows loops
          ·   Pad slanted to the right give rise to loop opening to the left and vice versa.
          ·  Small indistinct pads (flat pad) give rise to arches.
    Boundaries18 Nail furrow, flexion creases and margin of the fingertips Pattern ·  Act as obstacles to expansion and greatest stress form perpendicular to these obstacles.
    Markel cells18 Epiderrmal cell which are in contact with nerve endings Minutiae ·  The location of the Merkel cells determines minutiae
    Genetic25 Gene mutation and protein expression Ridges ·  Proper expression of SMARCAD1 may be important to ridge formation, and the disruption of its expression causes adermatoglyphia.
    Factors influencing fingerprints features

    APPLICATIONS OF FINGERPRINTS

    Forensic sciences

    The main driving force of using fingerprints is the uniqueness and consistency once formed. [4, 26]In addition, non-volatile inorganic component of eccrine secretion from fingerprints has been shown to remain intact even when exposed to temperatures as high as 600°C. 27The application of the new scanning Kelvin probe fingerprinting technique, which makes no physical contact with the fingerprint and does not require the use of developers, has the potential to allow fingerprints to be recorded whilst still leaving intact material that could subsequently be subjected to DNA analysis. [28, 29]The sole aim of using fingerprint is to establish identity. The identity can be informed of sex, ethnicity, and life style prediction.

    Sex determination

    The fingerprints have features which can be used to determine the sex of individuals. Using fingerprint patterns, it was reported that females have more arches, and males have more whorls. Males’ prints tend to have higher levels of urea than women's. 30Males were also reported to have coarser ridges than females by approximately10%. 31Females had a significantly higher ulnar ridge density in the right thumb among Hausa population of Kano state. 32It was reported that females had higher ridge counts in all the ulnar, radial and proximal areas among Mataco-Mataguayo 33Sudanese 34and Argentinian 35populations. On average females have finer ridge compared to their male counterparts.

    Ethnic differentiation

    A population-wise comparison demonstrated that ridge densities recorded amongAfricans (Sudanese and Nigerians). [32, 34] were lower than those reported among Argentinians. 35Spaniards 36and central Indians. 37, using the same methodology. This may give insights into the possible occurrence of lower ridge counts among people of African descent. 32. Confounding variables, such as age, need to be considered when making a comparison between sexes and the populations under study. This is because ridge density, which is permanent after formation, decreases with age and, at all ages, ridge density is higher on the distal (radial and ulnar) area, followed by the proximal sides. Females were found to have higher ridge density than males when older than 12 years, but not when younger in the Mataco-Mataguayo population.33This is consistent with changes in body composition and proportions, which differ among populations and depend more critically on sex at a specific age. 32

    Life style prediction

    Gelatine based tape and high-tech chemical analysis under spectroscopic microscope reveals the chemical- and metabolic make-up found on a fingerprint. The study revealed that specific amino acids indicated whether the “suspect” was a vegetarian ormeat-eater.30Spectroscopic microscope method based on the study of chemicals and metabolic featured with a fingerprint can also reveal the use of substances, including: cigarettes, drugs, grooming products etc. 30

    Risk of diseases

    The earliest scientist to explore the potential of fingerprints in clinical medicine was Cummins.38Fingerprints are used as a diagnostic tool in a number of diseases which have strong hereditary basis. [39, 40] Two different approaches are adopted a) Quantitative approach; this based on the fingerprints patterns, basically loops, arches and whorls. For example, there is decrease in frequency of ulnar loops and increase in arches in patients with cancer of the cervix. 41 b) Qualitative approach; this involves the ridge counts, total or absolute. [42, 43] (Schaumann and Alter, 1976; Chimne and Ksheersagar, 2012)for example in Klinefelter’s syndrome a total reduction of finger ridge count was reported. 44 Whereas increase in total finger ridge count was noticed in patients with essential hypertension. 45In general a remarkable improvement has been achieved in the concept of association of fingerprints and some individual disorders. [46, 47]However, it should be noted that the findings are population specific. A particular trait in a diseased population may be observed in a healthy population. For example, total ridge counts were prominently higher than the control group in both right and left hands of the female and male patients with multiple sclerosis (MS). 48On the contrary, in another population ridge counts in the fingertips of patients with MS were lower than the control group. 49In schizophrenia, these case subjects were found to have more number of arches and loops and less whorls50. In contrary, it was established that there was significant increase in whorls and decrease in loops in male schizophrenic patients. 51

    Conclusion

    The crucial events for the establishment of the epidermal ridge patterns take place from the 10th to 16th weeks of development. These established the future surface patterns which become well pronounced at the 16th week. Primary ridge formation does not occur simultaneously on volar skin surface. The different hypotheses were established which are key to the understanding of the embryology of the fingerprints. Although no universal accepted mechanisms for ridge formation exist, both environmental and genetic factors have role to play in the formation of the fingerprints. The primary aim of using fingerprints is for personal identification these can be achieved through revealing sex, diet and lifestyle of an individual. Fingerprints can also be used to establish risk of disease conditions. However, this potential is population specific and should be interpreted differently across different population.

    References

    1.Cummins H, Midlo C. (1976) Fingerprints, palms and soles.. Search at Google Scholar
    2.Galton F. (1892) . Search at Google Scholar
    3.Jain A, Y, Demirkus M. (2007) Pores and ridges: High-Resolution Fingerprint Matching Using Level 3 Features. IEEE Transac. Pattern Analy. Mach. Intell. 29(1), 15-27. Search at Google Scholar
    4.Babler W. (1991) Embryological development of epidermal ridges and their configuration.. 27, 95-112. Search at Google Scholar
    5.Bhat G, Mukhdoomi M, Shah B, Ittoo M. (2014) Molecular dermatoglyphics: in health and disease - a review.. Int. J. Res. Med. Sci. 2-31. Search at Google Scholar
    6.Bonnevie K. (1927) The crest development stages of the papillary arteries of the human finger ball.. Nyt. Mag. Naturvidensicaaberne. 65. Search at Google Scholar
    7.Gould E. Tulane University. (1948) A topographic study of the differentiation of the dermatoglyphic in the human embryo. PhD thesis.. Search at Google Scholar
    8.Hale A. (1951) Morphogenesis of volar skin in the human fetus.. Am. J. Anat. 91, 147-180. Search at Google Scholar
    9.Hirsch W. (1973) Morphological evidence concerning the problem of skin ridge formation.. J Ment. Defic. Res. 17, 58-72. Search at Google Scholar
    10.Okajima M. (1975) Development of dermal ridges in the fetus.. J. Med. Gen. 12, 234-250. Search at Google Scholar
    11.Penrose L, O’Hara P. (1973) The development of epidermal ridge.. J. Med. Gen. 10, 201-208. Search at Google Scholar
    12.Schaeuble J. (1932) The distention of the palmar triadii.. Z. Morphol. Anthropol. 31, 403-438. Search at Google Scholar
    13.Kucken M, Newell A. (2004) A model of fingerprints formation.. Euro Phy. Latt. 68(1), 141-146. Search at Google Scholar
    14.Hale A. (1949) Breadth of epidermal ridges in the fetus and its relation to the growth of hand and foot.. Anat. Rec. 105, 763-776. Search at Google Scholar
    15.Kollmann A.(1883) the tactile apparatus of the human races and the apes in its development and division.. Search at Google Scholar
    16.Cummins H. (1926) Epidermal ridge configuration in developmental defects, with particular reference to the ontogenetic factors which condition ridge direction.. Am. J. Anat. 38, 87-151. Search at Google Scholar
    17.Bonnevie K. (1932) On mechanic of papillary arm formation II.. Roux. Arch. of Dev. Biol. 126, 348-347. Search at Google Scholar
    18.Kucken M, Newell A. (2005) Fingerprints formation.. J Theoretical Biol. 235, 71-83. Search at Google Scholar
    19.Dell D, Munger B. (1986) The early embryogenesis of t papillary (sweat gland) ridges in primate glabrous skin: The dermatotopic map of cuteneous mechanoreceptors and dermatoglyphics.. J Compul. Neurol. 244, 511-532. Search at Google Scholar
    20.Moore S, Munger B. (1989) The early ontologeny of the afferent nerves and papillary ridges in human digital glabrous skin.. Dev. Brain Res. 48, 119-141. Search at Google Scholar
    21.Morohunfola K, Jones T, Munger B. (1992) The differentiation of the skin and its appendages II. Altered development of papillary ridges following nueralectomy.. Anat. Rec. 232, 599-611. Search at Google Scholar
    22.Bentil D, Murray J. (1993) On the mechanical theory for Biological pattern formation.. Physica 63, 161-190. Search at Google Scholar
    23.Diego A, Angelica M. (2011) A biochemical hypothesis on the formation of fingerprints using a turning patterns approach.. Theor. Biol. Med. Model. 8, 24. Search at Google Scholar
    24.Bonnevie K. (1929) What teaches the embryology of the papillary patterns about their meaningfulness as a race and family character. Part I and II. Z inducts.. Abstammver. 50, 219-274. Search at Google Scholar
    25.Adra C, Donato J, Badovinac R, Syed F, Kheraj R et al. (2001) SMARCAD1, a novel human helicase family-defining member associated with genetic instability: cloning, expression, and mapping to 4q22-q23, a band rich in breakpoints and deletion mutants involved in several human diseases.. Genomics 69(2), 162-73. Search at Google Scholar
    26.Cummins H, Midlo C. (1943) Finger, palm and sole prints. An introduction to dermatoglyphics, Second Ed.. Search at Google Scholar
    27.McMurray N, Williams G. Materials Research Centre. Swansea University. (2010) . Search at Google Scholar
    28.Ward M. (2006) Fingerprints hide lifestyle clues.. BBC. http://news.bbc.co.uk/1/hi/technology/4857114.stm. Retrieved . Search at Google Scholar
    29.SkyNews. (2006) Bombers Tracked By New Techniquehttp://news.sky.com/skynews/article/0,,31100-1218342,00.html. Retrieved. Search at Google Scholar
    30.Charles Q. (2007) New fingerprint Technique could reveal diet, sex, and race. Live Science.. Search at Google Scholar
    31.Kralik M, Novotny V. (2003) Epidermal ridge breadth: an indicator of age and sex in paleodermatoglyphics.. Variab. Evol.11:5–30. Search at Google Scholar
    32.Adamu L, Ojo S, Danborno B, Adebisi S, Taura M. (2016) Sexprediction using ridge density and thickness among the Hausa ethnic group of Kano state,Nigeria. Austr. J. Forensic Sci. 1-17. Search at Google Scholar
    33.Gutiérrez-Redomero E, Alonso M, E J. (2011) Sex differences in fingerprint ridge density in the Mataco-Mataguayo population.. HOMO – J. Comp. Hum. Biol. 62, 487-499. Search at Google Scholar
    34.Ahmed A, Osman S. (2016) Topological variability and sex differences in fingerprint ridge density in a sample of the Sudanese population. J Forensic Leg Med.. 42-25. Search at Google Scholar
    35.Rivalderia N, Sanchez-Andres A, Alonso-Rodriguez C, JE D, Gutierrez-Redomero E.Fingerprint ridge density in the Argentinean population and its application to sex inference: a comparative study.. HOMO. J Comp Hum Biol. 2016-67. Search at Google Scholar
    36.Gutiérrez-Redomero E, Alonso C, Romero E, Galera V. (2008) Variability of fingerprint ridge density in a sample of Spanish Caucasians and its application to sex determination. Forensic Sci.. Int. 180, 17-22. Search at Google Scholar
    37.Kapoor N, Badiye A. (2015) Sex differences in thumbprint ridge density in a central Indian population Egyptian.. J Forensic Sci. 5(1). Search at Google Scholar
    38.Cummins H. (1936) . Dermatoglyphics stigmata in Mangolisim. Anat. Rec. 64(suppl.2):11. . Search at Google Scholar
    39.M, Goldman B. (1982) Fetal dermatoglyphics.. Clin. Genet. 21-4. Search at Google Scholar
    40.Shiono H.Dermatoglyphics in Medicine.. Am. J. Forensic Med. Med. Pathol. 7-2. Search at Google Scholar
    41.Pal G, Roufal R, Bhagvat S. (1985) Dermatoglyphics in carcinoma cervix..J Ant Soc.. 34-3. Search at Google Scholar
    42.Schaumann B, Alter M. (1976) Dermatoglyphics in medical disorders.. 187-189. Search at Google Scholar
    43.Chimne H, Ksheersagar D. (2012) Dermatoglyphics in Angiographically proven coronary artery disease.. J Anat Soc India. 61-2. Search at Google Scholar
    44.Komotz Y, Yoshida O. (1976) Finger patterns and ridge counts of patients with Klinefelter’s syndrome (47xxy) among the Japanese, Hum Hered.. 26-4. Search at Google Scholar
    45.Pursani 9, Elhence G, Tibrewala L. (1989) Palmer dermatoglyphics in essential hypertension.. Indian heart J. 41-119. Search at Google Scholar
    46.Holt S. (1961) Dermatoglyphic pattern, Eds. Genitical variations in human populations.. 791. Search at Google Scholar
    47.Shamsuddin S, Masomi M, Magad. (1997) Relations between the lines on the fingers of hands and the incidence of disease in the human.. Journal of Kermin Medical Science University. 4-3. Search at Google Scholar
    48.Sabanciogullari V, Cevik S, Karacan K, Bolayir E, Cimen M. (2014) Dermatoglyphic features in patients with multiple sclerosis.. 19(4), 281-285. Search at Google Scholar
    49.Supe S, Milicić J, Pavićević R. (1997) Analysis of the quantitative dermatoglyphics of the digito-palmar complex in patients with multiple sclerosis.. Coll. Antropol. 21, 319-325. Search at Google Scholar
    50.Jhingan H, Munjal G. (1990) Dermatoglyphics In. Male Catatonic Schizophrenics, Indian J. Psychiat. 32(2), 188-192. Search at Google Scholar
    51.Pahuja K, Agarwal S. (2012) Analysis of quantitative and qualitative dermatoglyphic traits in Schizopherinic patients.. J Anat Soc of India. 61-2. Search at Google Scholar
    52.Muller-Ford C.(2004).Analysis of dermatoglyphic heritability: A study of phenotypic relationships".. Master of Arts the University of Montana. ProQuest LLC. 789 East Eisenhower Parkway P.O. Box 1346 Ann Arbor, Ml 48106 – 1346. Search at Google Scholar
    53.Jain A, Prabhakar S, Pankanti S. (2002) On the similarity of identical twin fingerprints.. Pattern Recog. 35:2653 – 2663. Search at Google Scholar